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HIV treatment as prevention: models, data, and questions--towards evidence-based decision-making.
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Title: | HIV treatment as prevention: models, data, and questions--towards evidence-based decision-making. |
Authors: | HIV Modelling Consortium Treatment as Prevention Editorial Writing Group |
Item Type: | Journal Article |
Abstract: | Antiretroviral therapy (ART) for those infected with HIV can prevent onward transmission of infection, but biological efficacy alone is not enough to guide policy decisions about the role of ART in reducing HIV incidence. Epidemiology, economics, demography, statistics, biology, and mathematical modelling will be central in framing key decisions in the optimal use of ART. PLoS Medicine, with the HIV Modelling Consortium, has commissioned a set of articles that examine different aspects of HIV treatment as prevention with a forward-looking research agenda. Interlocking themes across these articles are discussed in this introduction. We hope that this article, and others in the collection, will provide a foundation upon which greater collaborations between disciplines will be formed, and will afford deeper insights into the key factors involved, to help strengthen the support for evidence-based decision-making in HIV prevention. |
Issue Date: | 10-Jul-2012 |
Date of Acceptance: | 10-Jul-2012 |
URI: | http://hdl.handle.net/10044/1/48994 |
DOI: | https://dx.doi.org/10.1371/journal.pmed.1001259 |
ISSN: | 1549-1277 |
Publisher: | Public Library of Science |
Journal / Book Title: | PLOS Medicine |
Volume: | 9 |
Issue: | 7 |
Copyright Statement: | Public Domain. This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication (https://creativecommons.org/share-your-work/public-domain/cc0/). |
Keywords: | Antiretroviral Therapy, Highly Active Clinical Trials as Topic Decision Making Evidence-Based Medicine HIV Infections Humans Models, Biological HIV Modelling Consortium Treatment as Prevention Editorial Writing Group General & Internal Medicine 11 Medical And Health Sciences |
Publication Status: | Published |
Conference Place: | United States |
Article Number: | e1001259 |
Appears in Collections: | School of Public Health |