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Bariatric surgery or non-surgical weight loss for idiopathic intracranial hypertension? A systematic review and comparison of meta-analyses

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Title: Bariatric surgery or non-surgical weight loss for idiopathic intracranial hypertension? A systematic review and comparison of meta-analyses
Authors: Manfield, JH
Yu, KK-H
Efthimiou, E
Darzi, A
Athanasiou, T
Ashrafian, H
Item Type: Journal Article
Abstract: Background: Idiopathic intracranial hypertension (IIH) is associated with obesity and weight loss by any means is considered beneficial in this condition. Objectives: This study aims to appraise bariatric surgery vs. non-surgical weight-loss (medical, behavioural and lifestyle) interventions in IIH management. Methods: A systematic review and meta-analyses of surgical and non-surgical studies. Results: Bariatric surgery achieved 100% papilloedema resolution and a reduction in headache symptoms in 90.2%. Non-surgical methods offered improvement in papilloedema in 66.7%, visual field defects in 75.4% and headache symptoms in 23.2%. Surgical BMI decrease was 17.5 vs. 4.2 for non-surgical methods. Conclusions: Whilst both bariatric surgery and non-surgical weight loss offer significant beneficial effects on IIH symptomatology, future studies should address the lack of prospective and randomised trials to establish the optimal role for these interventions.
Issue Date: 15-Dec-2016
Date of Acceptance: 1-Dec-2016
URI: http://hdl.handle.net/10044/1/44583
DOI: https://dx.doi.org/10.1007/s11695-016-2467-7
ISSN: 0960-8923
Publisher: Springer
Start Page: 513
End Page: 521
Journal / Book Title: Obesity Surgery
Volume: 27
Issue: 2
Copyright Statement: © 2016 The Author(s). Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Keywords: Science & Technology
Life Sciences & Biomedicine
Surgery
Idiopathic intracranial hypertension
Pseudotumor cerebri
Benign intracranial hypertension
Obesity
Bariatric surgery
Metabolic surgery
Weight loss
PSEUDOTUMOR CEREBRI
TREATMENT TRIAL
MORBID-OBESITY
WOMEN
DIET
ACETAZOLAMIDE
THROMBOSIS
PRESSURE
HEADACHE
OUTCOMES
1103 Clinical Sciences
1117 Public Health And Health Services
Publication Status: Published
Appears in Collections:Department of Surgery and Cancer
Institute of Global Health Innovation