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Grand round: anticoagulation in chronic liver disease

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Title: Grand round: anticoagulation in chronic liver disease
Authors: Dhar, A
Mullish, BH
Thursz, MR
Item Type: Journal Article
Abstract: In this Grand Round, we first present a case of a man with decompensated liver disease who subsequently developed a fatal pulmonary embolism, having not been prescribed prophylactic anticoagulation to prevent venous thromboembolic disease. We go on to discuss the burden of thrombotic disease in those with chronic liver disease, before a more detailed discussion regarding the current evidence, safety data, and clinical dilemmas regarding the use of anticoagulation in patients with chronic liver disease, as well as discussing potential future directions within this field.
Issue Date: 12-Jan-2017
Date of Acceptance: 4-Jan-2017
URI: http://hdl.handle.net/10044/1/43943
DOI: https://dx.doi.org/10.1016/j.jhep.2017.01.006
ISSN: 1600-0641
Publisher: Elsevier
Start Page: 1313
End Page: 1326
Journal / Book Title: Journal of Hepatology
Volume: 66
Issue: 6
Copyright Statement: © 2016, Elsevier Ltd. All rights reserved. This manuscript is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/
Keywords: Anticoagulation
Cirrhosis
Direct oral anticoagulants
Heparin
Liver diseases
Teaching rounds
Thromboembolism
Thrombosis
Gastroenterology & Hepatology
1103 Clinical Sciences
Publication Status: Published
Conference Place: Netherlands
Appears in Collections:Department of Surgery and Cancer