An experimental investigation has been conducted into the degree of shear interaction between cold-formed steel floor joists and wood-based flooring panels and the resulting benefits derived in terms of composite action. A series of four-point bending tests have been carried out to evaluate the overall system behavior, while material tests have been performed to accurately define the material properties of each component of the examined system. Two different shear transfer mechanisms were examined: self-drilling screws with varying spacing and structural adhesive. The bare system was also tested to provide a reference response, against which the stiffness and capacity of the composite system could be bench-marked. The experiments showed that significant benefit could be derived as a result of composite action with as much as a 100% increase in bending capacity and 42% increase in stiffness.