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Reduced efficacy of praziquantel against Schistosoma mansoni is associated with multiple-rounds of mass drug administration
File | Description | Size | Format | |
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![]() | Accepted version | 1.33 MB | Microsoft Word | View/Open |
![]() | Published version | 695.2 kB | Adobe PDF | View/Open |
Title: | Reduced efficacy of praziquantel against Schistosoma mansoni is associated with multiple-rounds of mass drug administration |
Authors: | Crellen, T Walker, M Cotton, JA Lamberton, PHL Webster, JP Tukahebwa, EM Kabatereine, NB |
Item Type: | Journal Article |
Abstract: | The efficacy of praziquantel against Schistosoma mansoni was significantly lower in Ugandan schools that had received more prior rounds of mass drug administration, as determined by fitting a statistical model to parasite egg counts before and after treatment. |
Issue Date: | 28-Jul-2016 |
Date of Acceptance: | 21-Jul-2016 |
URI: | http://hdl.handle.net/10044/1/38381 |
DOI: | https://dx.doi.org/10.1093/cid/ciw506 |
ISSN: | 1537-6591 |
Publisher: | Oxford University Press (OUP) |
Start Page: | 1151 |
End Page: | 1159 |
Journal / Book Title: | Clinical Infectious Diseases |
Volume: | 63 |
Issue: | 9 |
Copyright Statement: | © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
Sponsor/Funder: | World Health Organization World Health Organization (Switzerland) |
Funder's Grant Number: | World Health Organization 2015/540029-0 |
Keywords: | anthelmintic efficacy generalized linear mixed model parasite praziquantel schistosomiasis Microbiology 06 Biological Sciences 11 Medical And Health Sciences |
Publication Status: | Published |
Appears in Collections: | School of Public Health |