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Linking apoptosis to cancer metabolism: Another missing piece of JuNK

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Title: Linking apoptosis to cancer metabolism: Another missing piece of JuNK
Authors: Papa, S
Bubici, C
Item Type: Journal Article
Abstract: Cancer cells become dependent on aerobic glycolysis to sustain rapid proliferation and escape apoptosis. How this metabolic change, also known as the Warburg effect, is linked to apoptosis remains largely unknown. Our new data place c-Jun N-terminal kinase in the center of a hub regulating apoptosis and cancer metabolism.
Issue Date: 4-Apr-2016
Date of Acceptance: 30-Sep-2015
URI: http://hdl.handle.net/10044/1/32694
DOI: https://dx.doi.org/10.1080/23723556.2015.1103398
ISSN: 2372-3556
Publisher: Taylor & Francis
Journal / Book Title: Molecular & Cellular Oncology
Volume: 3
Issue: 2
Copyright Statement: © 2016 The Author(s). Published with license by Taylor & Francis Group, LLC© Salvatore Papa and Concetta Bubici. This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License http://creativecommons.org/licenses/by-nc/3.0/, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
Sponsor/Funder: Kay Kendall Leukemia Fund
Funder's Grant Number: KKL443
Publication Status: Published
Article Number: e1103398
Appears in Collections:Department of Surgery and Cancer