Cigarette smoke induced airway inflammation is independent of NF-kappa B signalling

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Title: Cigarette smoke induced airway inflammation is independent of NF-kappa B signalling
Authors: Rastrick, JMD
Stevenson, CS
Eltom, S
Grace, M
Davies, M
Kilty, I
Evans, SM
Pasparakis, M
Catley, MC
Lawrence, T
Adcock, IM
Belvisi, MG
Birrell, MA
Item Type: Journal Article
Issue Date: 22-Jan-2013
Date of Acceptance: 5-Dec-2012
URI: http://hdl.handle.net/10044/1/31760
DOI: http://dx.doi.org/10.1371/journal.pone.0054128
ISSN: 1932-6203
Publisher: Public Library of Science
Journal / Book Title: PLOS One
Volume: 8
Issue: 1
Copyright Statement: © 2013 Rastrick et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Sponsor/Funder: Medical Research Council (MRC)
Medical Research Council (MRC)
Funder's Grant Number: G0800196
G0800195
Keywords: Science & Technology
Multidisciplinary Sciences
Science & Technology - Other Topics
MULTIDISCIPLINARY SCIENCES
OBSTRUCTIVE PULMONARY-DISEASE
INDUCED LUNG INFLAMMATION
BETA-DEPENDENT GENES
IKK-BETA
MOUSE LUNG
CHRONIC-BRONCHITIS
INDUCED EMPHYSEMA
OXIDATIVE STRESS
EPITHELIAL-CELLS
FLOW LIMITATION
Amides
Animals
Cells, Cultured
Disease Models, Animal
Epithelial Cells
Gene Expression
Humans
I-kappa B Kinase
Immunohistochemistry
Inflammation
Lipopolysaccharides
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
NF-kappa B
Pulmonary Disease, Chronic Obstructive
Respiratory Tract Diseases
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction
Smoke
Smoking
Thiophenes
Time Factors
Tobacco
Transcription Factor RelA
General Science & Technology
MD Multidisciplinary
Publication Status: Published
Article Number: e54128
Appears in Collections:National Heart and Lung Institute
Airway Disease
Faculty of Medicine



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