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Brd4 is essential for IL-1 beta-induced inflammation in human airway epithelial cells

Title: Brd4 is essential for IL-1 beta-induced inflammation in human airway epithelial cells
Authors: Khan, YM
Kirkham, P
Barnes, PJ
Adcock, IM
Item Type: Journal Article
Issue Date: 23-Apr-2014
Date of Acceptance: 23-Mar-2014
URI: http://hdl.handle.net/10044/1/31735
DOI: http://dx.doi.org/10.1371/journal.pone.0095051
ISSN: 1932-6203
Publisher: Public Library of Science
Journal / Book Title: PLOS One
Volume: 9
Issue: 4
Copyright Statement: © 2014 Khan et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Sponsor/Funder: Medical Research Council (MRC)
Funder's Grant Number: G1000758
Keywords: Science & Technology
Multidisciplinary Sciences
Science & Technology - Other Topics
MULTIDISCIPLINARY SCIENCES
OBSTRUCTIVE PULMONARY-DISEASE
NF-KAPPA-B
BET BROMODOMAIN INHIBITION
EXPIRED BREATH CONDENSATE
RNA-POLYMERASE-II
OXIDATIVE STRESS
HISTONE ACETYLATION
GLUCOCORTICOID-RECEPTOR
GENE-EXPRESSION
TRANSCRIPTIONAL ELONGATION
Azepines
Cell Line
Chromatin Immunoprecipitation
Enzyme-Linked Immunosorbent Assay
Epithelial Cells
Humans
Hydrogen Peroxide
Inflammation
Interleukin-1beta
Interleukin-6
Interleukin-8
Nuclear Proteins
Protein-Serine-Threonine Kinases
Transcription Factors
Triazoles
General Science & Technology
MD Multidisciplinary
Publication Status: Published
Article Number: e95051
Appears in Collections:National Heart and Lung Institute
Airway Disease
Faculty of Medicine



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