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Tumour necrosis factor-alpha regulates human rosinophil apoptosis via ligation of TNF-receptor 1 and balance between NF-kappa B and AP-1

Title: Tumour necrosis factor-alpha regulates human rosinophil apoptosis via ligation of TNF-receptor 1 and balance between NF-kappa B and AP-1
Authors: Kankaanranta, H
Ilmarinen, P
Zhang, X
Adcock, IM
Lahti, A
Barnes, PJ
Giembycz, MA
Lindsay, MA
Moilanen, E
Item Type: Journal Article
Issue Date: 28-Feb-2014
Date of Acceptance: 2-Feb-2014
URI: http://hdl.handle.net/10044/1/31703
DOI: http://dx.doi.org/10.1371/journal.pone.0090298
ISSN: 1932-6203
Publisher: Public Library of Science
Journal / Book Title: PLOS One
Volume: 9
Issue: 2
Copyright Statement: © 2014 Kankaanranta et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Sponsor/Funder: Medical Research Council (MRC)
Funder's Grant Number: G1000758
Keywords: Science & Technology
Multidisciplinary Sciences
Science & Technology - Other Topics
MULTIDISCIPLINARY SCIENCES
IN-VITRO
CELL LIFE
C-JUN
ACTIVATION
ASTHMA
INHIBITION
SURVIVAL
KINASE
DEATH
JNK
Antibodies
Antigens, CD95
Apoptosis
Asthma
Cell Survival
Eosinophils
Gene Expression Regulation
Gliotoxin
Humans
I-kappa B Kinase
Imidazoles
NF-kappa B
Phosphorylation
Primary Cell Culture
Protein Binding
Pyrrolidines
Quinoxalines
Receptors, Tumor Necrosis Factor, Type I
Retinoids
Signal Transduction
Thiocarbamates
Transcription Factor AP-1
Tumor Necrosis Factor-alpha
General Science & Technology
MD Multidisciplinary
Publication Status: Published
Article Number: e90298
Appears in Collections:National Heart and Lung Institute
Airway Disease
Faculty of Medicine



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