Influence of left atrial geometry on rotor core trajectories in a model of atrial fibrillation

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Title: Influence of left atrial geometry on rotor core trajectories in a model of atrial fibrillation
Authors: Tzortzis, KN
Roney, CH
Qureshi, NA
Ng, FU
Lim, PHANGBOON
Sherwin, S
Peters, NS
Cantwell, C
Item Type: Conference Paper
Abstract: © 2015 CCAL.Left atrial anatomy and myocardial architecture are known to influence rotor initiation and maintenance. However, identifying their relative contribution clinically is challenging. The present study aims to investigate in silico the effect of left atrial geometry in isolation on rotor generation and evolution through the spatiotemporal tracking of phase singularities. After meandering for a short period of time, rotors are attracted to specific areas of the chamber where there is high curvature, primarily near the base of the left atrial appendage and the junctions of the pulmonary veins. This suggests that the left atrial anatomy could play a key role in the perpetuation of fibrillatory activity.
Issue Date: 9-Sep-2015
Date of Acceptance: 1-Sep-2015
URI: http://hdl.handle.net/10044/1/31456
DOI: https://dx.doi.org/10.1109/CIC.2015.7408691
ISBN: 978-1-5090-0685-4
ISSN: 2325-8861
Publisher: IEEE
Start Page: 481
End Page: 484
Journal / Book Title: Computing in Cardiology
Issue: 42
Copyright Statement: © 2015 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Sponsor/Funder: British Heart Foundation
Engineering & Physical Science Research Council (E
British Heart Foundation
Funder's Grant Number: RE/08/002
EP/L000407/1
Conference Name: Computing in Cardiology
Publication Status: Published
Start Date: 2015-09-06
Finish Date: 2015-09-09
Conference Place: Nice, France
Appears in Collections:National Heart and Lung Institute
Aeronautics
Faculty of Medicine



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