New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Title:	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
Authors:	Dupuis, J Langenberg, C Prokopenko, I Saxena, R Soranzo, N Jackson, AU Wheeler, E Glazer, NL Bouatia-Naji, N Gloyn, AL Lindgren, CM Magi, R Morris, AP Randall, J Johnson, T Elliott, P Rybin, D Thorleifsson, G Steinthorsdottir, V Henneman, P Grallert, H Dehghan, A Hottenga, JJ Franklin, CS Navarro, P Song, K Goel, A Perry, JRB Egan, JM Lajunen, T Grarup, N Sparso, T Doney, A Voight, BF Stringham, HM Li, M Kanoni, S Shrader, P Cavalcanti-Proenca, C Kumari, M Qi, L Timpson, NJ Gieger, C Zabena, C Rocheleau, G Ingelsson, E An, P O'Connell, J Luan, J Elliott, A McCarroll, SA Payne, F Roccasecca, RM Pattou, F Sethupathy, P Ardlie, K Ariyurek, Y Balkau, B Barter, P Beilby, JP Ben-Shlomo, Y Benediktsson, R Bennett, AJ Bergmann, S Bochud, M Boerwinkle, E Bonnefond, A Bonnycastle, LL Borch-Johnsen, K Boettcher, Y Brunner, E Bumpstead, SJ Charpentier, G Chen, Y-DI Chines, P Clarke, R Coin, LJM Cooper, MN Cornelis, M Crawford, G Crisponi, L Day, INM De Geus, EJC Delplanque, J Dina, C Erdos, MR Fedson, AC Fischer-Rosinsky, A Forouhi, NG Fox, CS Frants, R Franzosi, MG Galan, P Goodarzi, MO Graessler, J Groves, CJ Grundy, S Gwilliam, R Gyllensten, U Hadjadj, S Hallmans, G Hammond, N Han, X Hartikainen, A-L Hassanali, N Hayward, C Heath, SC Hercberg, S Herder, C Hicks, AA Hillman, DR Hingorani, AD Hofman, A Hui, J Hung, J Isomaa, B Johnson, PRV Jorgensen, T Jula, A Kaakinen, M Kaprio, J Kesaniemi, YA Kivimaki, M Knight, B Koskinen, S Kovacs, P Kyvik, KO Lathrop, GM Lawlor, DA Le Bacquer, O Lecoeur, C Li, Y Lyssenko, V Mahley, R Mangino, M Manning, AK Teresa Martinez-Larrad, M McAteer, JB McCulloch, LJ McPherson, R Meisinger, C Melzer, D Meyre, D Mitchell, BD Morken, MA Mukherjee, S Naitza, S Narisu, N Neville, MJ Oostra, BA Orru, M Pakyz, R Palmer, CNA Paolisso, G Pattaro, C Pearson, D Peden, JF Pedersen, NL Perola, M Pfeiffer, AFH Pichler, I Polasek, O Posthuma, D Potter, SC Pouta, A Province, MA Psaty, BM Rathmann, W Rayner, NW Rice, K Ripatti, S Rivadeneira, F Roden, M Rolandsson, O Sandbaek, A Sandhu, M Sanna, S Sayer, AA Scheet, P Scott, LJ Seedorf, U Sharp, SJ Shields, B Sigurosson, G Sijbrands, EJG Silveira, A Simpson, L Singleton, A Smith, NL Sovio, U Swift, A Syddall, H Syvanen, A-C Tanaka, T Thorand, B Tichet, J Tonjes, A Tuomi, T Uitterlinden, AG Van Dijk, KW Van Hoek, M Varma, D Visvikis-Siest, S Vitart, V Vogelzangs, N Waeber, G Wagner, PJ Walley, A Walters, GB Ward, KL Watkins, H Weedon, MN Wild, SH Willemsen, G Witteman, JCM Yarnell, JWG Zeggini, E Zelenika, D Zethelius, B Zhai, G Zhao, JH Zillikens, MC Borecki, IB Loos, RJF Meneton, P Magnusson, PKE Nathan, DM Williams, GH Hattersley, AT Silander, K Salomaa, V Smith, GD Bornstein, SR Schwarz, P Spranger, J Karpe, F Shuldiner, AR Cooper, C Dedoussis, GV Serrano-Rios, M Morris, AD Lind, L Palmer, LJ Hu, FB Franks, PW Ebrahim, S Marmot, M Kao, WHL Pankow, JS Sampson, MJ Kuusisto, J Laakso, M Hansen, T Pedersen, O Pramstaller, PP Wichmann, HE Illig, T Rudan, I Wright, AF Stumvoll, M Campbell, H Wilson, JF Bergman, RN Buchanan, TA Collins, FS Mohlke, KL Tuomilehto, J Valle, TT Altshuler, D Rotter, JI Siscovick, DS Penninx, BWJH Boomsma, DI Deloukas, P Spector, TD Frayling, TM Ferrucci, L Kong, A Thorsteinsdottir, U Stefansson, K Van Duijn, CM Aulchenko, YS Cao, A Scuteri, A Schlessinger, D Uda, M Ruokonen, A Jarvelin, M-R Waterworth, DM Vollenweider, P Peltonen, L Mooser, V Abecasis, GR Wareham, NJ Sladek, R Froguel, P Watanabe, RM Meigs, JB Groop, L Boehnke, M McCarthy, MI Florez, JC Barroso, I
Item Type:	Journal Article
Issue Date:	1-Feb-2010
Date of Acceptance:	14-Oct-2009
URI:	http://hdl.handle.net/10044/1/28921
DOI:	https://dx.doi.org/10.1038/ng.520
ISSN:	1546-1718
Publisher:	Nature Publishing Group
Start Page:	105
End Page:	U32
Journal / Book Title:	Nature Genetics
Volume:	42
Issue:	2
Copyright Statement:	© 2010, Rights Managed by Nature Publishing Group
Sponsor/Funder:	Medical Research Council (MRC) Medical Research Council (MRC) Medical Research Council (MRC)
Funder's Grant Number:	G0600331 G0801056B G0801056/1
Keywords:	Science & Technology Life Sciences & Biomedicine Genetics & Heredity GENETICS & HEREDITY GENOME-WIDE ASSOCIATION BETA-CELL DYSFUNCTION PLASMA-GLUCOSE INSULIN-SECRETION TRIGLYCERIDE LEVELS ESSENTIAL COMPONENTS MODEL ASSESSMENT COMMON VARIANTS CIRCADIAN CLOCK DISEASE RISK Adolescent Adult Alleles Blood Glucose Child DNA Copy Number Variations Databases, Genetic Diabetes Mellitus, Type 2 Fasting Gene Expression Regulation Genetic Loci Genetic Predisposition to Disease Genome-Wide Association Study Homeostasis Humans Meta-Analysis as Topic Polymorphism, Single Nucleotide Quantitative Trait Loci Quantitative Trait, Heritable Reproducibility of Results DIAGRAM Consortium GIANT Consortium Global BPgen Consortium Anders Hamsten on behalf of Procardis Consortium MAGIC investigators Developmental Biology 11 Medical And Health Sciences 06 Biological Sciences
Publication Status:	Published
Appears in Collections:	National Heart and Lung Institute