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New genetic loci link adipose and insulin biology to body fat distribution

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Title: New genetic loci link adipose and insulin biology to body fat distribution
Authors: Shungin, D
Winkler, TW
Croteau-Chonka, DC
Ferreira, T
Lockes, AE
Maegi, R
Strawbridge, RJ
Pers, TH
Fischer, K
Justice, AE
Workalemahu, T
Nolte, IM
Olden, M
Montgomery, GW
Rayner, NW
Froguel, P
Gharavi, AG
Drong, AW
Kuulasmaa, K
Wilsgaard, T
Loos, RJF
Albrecht, E
Dedoussis, G
Renstrom, F
Ried, JS
Robertson, NR
Willer, CJ
Rose, LM
Sanna, S
Tremoli, E
Scharnagl, H
Scholtens, S
Arnlov, J
Lyssenko, V
Sennblad, B
Grabe, H-J
Hattersley, AT
Wojczynski, MK
Murabito, JM
Seufferlein, T
Brennan, EP
Sitlani, CM
Vohl, M-C
Lindstrom, J
Visscher, PM
Schwarz, PEH
Song, C
Wong, A
Hveem, K
Deelen, J
Vedantam, S
Day, FR
Bornstein, SR
Zhang, Q
Arscott, GM
Olsson, C
Garcia, ME
Hivert, M-F
Perry, JRB
Hayward, C
Lakka, TA
Reinmaa, E
Kutalik, Z
Salem, RM
Kuh, D
Keinanen-Kiukaanniemi, SM
Deelman, E
Sandholm, N
Kinnunen, L
Assimes, TL
Voelker, U
Leander, K
Schadt, EE
Scott, RA
Stolk, L
Vallejo, EE
Hillege, HL
Westra, H-J
Zondervan, KT
Mannisto, S
Langenberg, C
Berndt, SI
Delgado, G
Vollenweider, P
Heikkila, K
Amouyel, P
Arveiler, D
Bandinelli, S
Yang, J
Joeckel, K-H
Luan, J
Bakker, SJL
Beilby, J
Boehnkes, M
Heliovaara, M
Bergman, RN
Eriksson, JG
Blangero, J
McPherson, R
Kooperberg, C
Brown, MJ
Burnier, M
Le Marchand, L
Campbell, H
Hirschhorn, JN
Johansen, B
Herzig, K-H
Kivimaki, M
Hicks, AA
Graessler, J
Demirkan, A
Chakravarti, A
Chiness, PS
Claudi-Boehmi, S
Doney, ASF
Randall, JC
Collins, FS
Borecki, IB
Crawford, DC
Danesh, J
Munroe, PB
De Faire, U
Zillikens, MC
Wilson, JF
Hingorani, AD
Lehtimaki, T
De Geusl, EJC
Humphries, SE
Doerr, M
Deloukas, P
Eklund, N
Wareham, NJ
Helmer, Q
Hoffmann, W
North, KE
Stringham, HM
Juliusdottir, T
Holmen, O
Qi, L
Hofman, A
Marette, A
Tomaschitz, A
Jula, AM
Fehrmann, R
Choi, M
Laakso, M
Matise, TC
Wu, JMW
McKenzie, CA
Franks, PW
Sundstrom, J
McKnight, B
Liang, L
Barrett, A
Franke, L
Fall, T
Musk, AW
Mohlenkamp, S
Morris, AD
Nelis, M
Ohlsson, C
Oldehinkel, AJ
Njolstad, I
Amin, N
Bellis, C
Swertz, MA
Frayling, TM
Eriksson, P
Ong, KK
Karjalainen, J
Erdos, MR
Fox, CS
Ittermann, T
Palmer, LJ
Penninx, BW
Bennett, AJ
Witteman, JC
Peters, A
Shuldiner, AR
Pramstaller, PP
Hamsten, A
Raitakari, OT
Rankinen, T
Liu, Y
Rao, DC
Estrada, K
Chasman, DI
Folkersen, L
Barroso, I
Adair, LS
Lorentzon, M
Rice, TK
Ridker, PM
Ritchie, MD
Swift, AJ
James, AL
Kahali, B
Berne, C
Rudan, I
Salomaa, V
Samani, NJ
Eury, E
Groop, LC
Schmidt, EM
Maerz, W
Saramies, J
Bouchard, C
Sarzynski, MA
Blueher, M
Syvanen, A-C
Franco-Cereceda, A
Bochud, M
Giedraitis, V
Farrall, M
Keildson, S
Hedman, AK
Clarke, R
Boehm, BO
Oostra, BA
Gieger, C
Koenig, W
Hyppoenen, E
Ingelsson, E
Palmer, CNA
Hartman, CA
Pedersen, NL
Golay, A
Ferrannini, E
Perola, M
Kovacs, P
Buhringer, S
Isaacs, A
Perusse, L
Peters, U
Anderson, D
Power, C
Quertermous, T
Rauramaa, R
Cupples, LA
Lee, NR
Scherag, A
Bonnet, F
Illig, T
Rivadeneira, F
Kooner, IK
Tayo, BO
Gigante, B
Huang, J
Saaristo, TE
Saleheen, D
Buyske, S
Sinisalo, J
Watkins, H
Slagboom, PE
McCarthy, MI
Snieder, H
Spector, TD
Ehret, GB
Beekman, M
Thorand, B
Jarvelin, M-R
Go, AS
Hunter, DJ
Nicholson, G
Thorsteinsdottir, UR
Stumvoll, M
Tuomilehto, J
Ferrieres, J
Kanoni, S
Kratzer, W
Uitterlinden, AG
Uusitupa, M
Van der Harst, P
Thorleifsson, G
Boettcher, Y
Buchkovich, ML
Heid, IM
Veronesi, G
Schlessinger, D
Walker, M
Forouhi, NG
Wood, AR
Kaplan, RC
Troffa, C
Staessen, JA
Kooner, JS
Jousilahti, P
Smith, AV
O'Connell, JR
Morris, AP
Lifton, RP
Cauchi, S
Grallert, H
Lindgren, CM
Zhao, JH
Mohlke, KL
Vonk, JM
Steinthorsdottir, V
Feitosa, MF
Hui, J
Esko, T
Goel, A
Jackson, AU
Lichtner, P
Johnson, T
Kleber, ME
Kristiansson, K
Grewal, J
Metspalu, A
Johansson, I
Caulfield, MJ
Mangino, M
Ma, B
Forrester, T
Van Oort, FVA
Kaprio, J
Leach, IM
Medina-Gomez, C
Lobbens, S
Palmer, CD
Pasko, D
Friedrichs, N
Pechlivaniss, S
Peters, MJ
Mach, F
Lind, L
Franco, OH
Chambers, JC
Verweij, N
Bruinenberg, M
Prokopenko, I
Stancakova, A
Sung, YJ
Stolk, RP
Kee, F
McKnight, AJ
Tanakam, T
Teumer, A
Van Vliet-Ostaptchouk, JV
Gansevoort, RT
Hassinen, M
Grammer, TB
Yengo, L
Daw, EW
Zhang, W
Liu, C-T
Kalafati, I-P
Carba, DB
Gudnason, V
Bragg-Gresham, JL
Cooper, RS
Erbel, R
Caspersen, IH
Groves, CJ
Kraja, AT
Strachan, DP
Waite, LL
Haller, T
Homuth, G
Hallmans, G
Wichmann, H-E
Magnusson, PKE
Speliotes, EK
Hunt, SC
Mahajan, A
Heard-Costa, NL
Min, JL
McArdle, WL
Menni, C
Merger, S
Kuusisto, J
Karpe, F
Stefansson, K
Mihailov, E
Chen, J
Strauch, K
Haiman, CA
Absher, D
Milani, L
Mills, R
Moayyeri, A
Monda, KL
Gustafsson, S
Mooijaart, SP
Muehleisen, TW
Nyholt, DR
Moffatt, MF
Toenjes, A
Van Dujin, CM
Harris, TB
Roman, TS
Mulas, A
Mueller, G
Abecasis, GR
Ferrucci, L
Kumari, M
Mueller-Nurasyid, M
Nagaraja, R
Nalls, MA
Tremblay, A
Wennauer, R
Narisu, N
Stirrups, K
Glorioso, N
Lamina, C
Kiryluk, K
Item Type: Journal Article
Issue Date: 12-Feb-2015
URI: http://hdl.handle.net/10044/1/28734
DOI: https://dx.doi.org/10.1038/nature14132
ISSN: 0028-0836
Publisher: Nature Publishing Group
Start Page: 187
End Page: 196
Journal / Book Title: Nature
Volume: 518
Issue: 7538
Copyright Statement: © 2015 Macmillan Publishers Limited. All rights reserved
Keywords: Science & Technology
Multidisciplinary Sciences
Science & Technology - Other Topics
Genome-wide association
Mesenchymal stem-cells
Human height
Adipogenic differentiation
Abdominal adiposity
Susceptibility loci
Sexual-dimorphism
Glycemic traits
False discovery
Common SNPS
Adipocytes
Adipogenesis
Adipose Tissue
Age Factors
Body Fat Distribution
Body Mass Index
Continental Population Groups
Epigenesis, Genetic
Europe
Insulin
Insulin Resistance
Models, Biological
Neovascularization, Physiologic
Obesity
Polymorphism, Single Nucleotide
Quantitative Trait Loci
Sex Characteristics
Transcription, Genetic
Waist-Hip Ratio
ADIPOGen Consortium
CARDIOGRAMplusC4D Consortium
CKDGen Consortium
GEFOS Consortium
GENIE Consortium
GLGC
ICBP
International Endogene Consortium
LifeLines Cohort Study
MAGIC Investigators
MuTHER Consortium
PAGE Consortium
ReproGen Consortium
Genome, Human
General Science & Technology
Publication Status: Published
Appears in Collections:National Heart and Lung Institute