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siRNA Knockdown of Ribosomal Protein Gene RPL19 Abrogates the Aggressive Phenotype of Human Prostate Cancer

Title: siRNA Knockdown of Ribosomal Protein Gene RPL19 Abrogates the Aggressive Phenotype of Human Prostate Cancer
Authors: Bee, A
Brewer, D
Beesley, C
Dodson, A
Forootan, S
Dickinson, T
Gerard, P
Lane, B
Yao, S
Cooper, CS
Djamgoz, MBA
Gosden, CM
Ke, Y
Foster, CS
Item Type: Journal Article
Issue Date: 22-Jul-2011
URI: http://hdl.handle.net/10044/1/27626
DOI: https://dx.doi.org/10.1371/journal.pone.0022672
ISSN: 1932-6203
Publisher: PUBLIC LIBRARY SCIENCE
Journal / Book Title: PLOS ONE
Volume: 6
Issue: 7
Copyright Statement: © 2011 Bee et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Keywords: Science & Technology
Life Sciences & Biomedicine
Biology
Life Sciences & Biomedicine - Other Topics
DIAMOND-BLACKFAN ANEMIA
EPITHELIAL-STROMAL INTERACTIONS
HIGH-LEVEL EXPRESSION
CELL-LINE PC-3
BREAST-CANCER
SIALIC-ACID
DIFFERENTIAL EXPRESSION
EUKARYOTIC RIBOSOME
COLORECTAL-CANCER
MESSENGER-RNA
Notes: REF2004-A1 Pathophysiology and clinical management of prostate cancer remains a major problem in the western (and increasingly in the eastern) world. This paper is important as it reports the identification and characterization of a novel gene contributing to the cancer agressiveness.
Article Number: ARTN e22672
Appears in Collections:Faculty of Natural Sciences