Using biomaterials to rewire the process of wound repair
File(s)
Author(s)
Stejskalova, A
Almquist, BD
Type
Journal Article
Abstract
Wound healing is one of the most complex processes that our bodies must perform. While our ability to repair wounds is often taken for granted, conditions such as diabetes, obesity, or simply old age can significantly impair this process. With the incidence of all three predicted to continue growing into the foreseeable future, there is an increasing push to develop strategies that facilitate healing. Biomaterials are an attractive approach for modulating all aspects of repair, and have the potential to steer the healing process towards regeneration. In this review, we will cover recent advances developing biomaterials that actively modulate the process of wound healing, and will provide insight into how biomaterials can be used to simultaneously rewire multiple phases of the repair process.
Date Issued
2017-06-22
Date Acceptance
2017-06-22
ISSN
2047-4849
Publisher
Royal Society of Chemistry
Start Page
1421
End Page
1434
Journal / Book Title
Biomaterials Science
Volume
5
Copyright Statement
© The Royal Society of Chemistry 2017. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (https://creativecommons.org/licenses/by/3.0/)
Sponsor
Wellcome Trust
Wellcome Trust
Rosetrees Trust
Rosetrees Trust
Diabetes Research & Wellness Foundation
Grant Number
109838/Z/15/Z
109838/Z/15/Z
A1071
A1071
1770
Subjects
Science & Technology
Technology
Materials Science, Biomaterials
Materials Science
MESENCHYMAL STEM-CELLS
RECEPTOR TYROSINE KINASES
GROWTH-FACTOR RECEPTOR
PLATELET LYSATE
IN-VITRO
INFLAMMATORY RESPONSE
EXTRACELLULAR-MATRIX
TISSUE REGENERATION
DIABETIC WOUNDS
LIPID MEDIATORS
Publication Status
Published