Candidalysin is a fungal peptide toxin critical for mucosal infection

Moyes, DL; Wilson, D; Richardson, JP; Mogavero, S; Tang, SX; Wernecke, J; Hoefs, S; Gratacap, RL; Robbins, J; Runglall, M; Murciano, C; Blagojevic, M; Thavaraj, S; Foerster, TM; Hebecker, B; Kasper, L; Vizcay, G; Iancu, SI; Kichik, N; Haeder, A

doi:https://www.dx.doi.org/10.1038/nature17625

File(s)

Moyes16nature.pdf (649.75 KB)

Accepted version

Author(s)

Moyes, DL

Wilson, D

Richardson, JP

Mogavero, S

Tang, SX

more

Type

Journal Article

Date Issued

2016-03-30

Date Acceptance

2016-02-26

Citation

Nature, 2016, 532 (7597), pp.64-68

URI

http://hdl.handle.net/10044/1/38629

DOI

https://www.dx.doi.org/10.1038/nature17625

ISSN

0028-0836

Publisher

Nature Publishing Group

Start Page

64

End Page

68

Journal / Book Title

Nature

Volume

532

Issue

7597

Copyright Statement

Sponsor

Biotechnology and Biological Sciences Research Council (BBSRC)

Grant Number

BB/K003887/1

Subjects

Science & Technology

Multidisciplinary Sciences

Science & Technology - Other Topics

PROTEIN-KINASE HOMOLOG

SACCHAROMYCES-CEREVISIAE

HYPHAL DEVELOPMENT

EPITHELIAL-CELLS

OROPHARYNGEAL CANDIDIASIS

PATHOGENICITY MECHANISMS

TRANSCRIPTION FACTOR

BETA-MANNOSYLATION

FILAMENTOUS GROWTH

ALBICANS ENCODES

Calcium

Candida albicans

Candidiasis

Cell Membrane Permeability

Cytotoxins

Epithelial Cells

Fungal Proteins

Host-Pathogen Interactions

Humans

Mucous Membrane

Mycotoxins

Signal Transduction

Virulence

Virulence Factors

General Science & Technology

MD Multidisciplinary

Publication Status

Published