Accuracy of self-reported HIV testing history and awareness of HIV-positive status among people living with HIV in four Sub-Saharan African countries
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Supporting information
Accepted version
Author(s)
Type
Journal Article
Abstract
Background:
In many countries in Sub-Saharan Africa, self-reported HIV testing history and awareness of HIV-positive status from household surveys are used to estimate the percentage of people living with HIV (PLHIV) who know their HIV status. Despite widespread use, there is limited empirical information on the sensitivity of those self-reports, which can be affected by non-disclosure.
Methods:
Bayesian latent class models were used to estimate the sensitivity of self-reported HIV testing history and awareness of HIV-positive status in four Population-based HIV Impact Assessment surveys in Eswatini, Malawi, Tanzania, and Zambia. Antiretroviral (ARV) metabolites biomarkers were used to identify persons on treatment who did not accurately report their status. For those without ARV biomarkers, the pooled estimate of non-disclosure among untreated persons was 1.48 higher than those on treatment.
Results:
Among PLHIV, the model-estimated sensitivity of self-reported HIV testing history ranged from 96% to 99% across surveys. The model-estimated sensitivity of self-reported awareness of HIV status varied from 91% to 97%. Non-disclosure was generally higher among men and those aged 15–24 years. Adjustments for imperfect sensitivity did not substantially influence estimates of PLHIV ever tested (difference <4%) but the proportion of PLHIV aware of their HIV-positive status was higher than the unadjusted proportion (difference <8%).
Conclusions:
Self-reported HIV testing histories in four Eastern and Southern African countries are generally robust although adjustment for non-disclosure increases estimated awareness of status. These findings can contribute to further refinements in methods for monitoring progress along the HIV testing and treatment cascade.
In many countries in Sub-Saharan Africa, self-reported HIV testing history and awareness of HIV-positive status from household surveys are used to estimate the percentage of people living with HIV (PLHIV) who know their HIV status. Despite widespread use, there is limited empirical information on the sensitivity of those self-reports, which can be affected by non-disclosure.
Methods:
Bayesian latent class models were used to estimate the sensitivity of self-reported HIV testing history and awareness of HIV-positive status in four Population-based HIV Impact Assessment surveys in Eswatini, Malawi, Tanzania, and Zambia. Antiretroviral (ARV) metabolites biomarkers were used to identify persons on treatment who did not accurately report their status. For those without ARV biomarkers, the pooled estimate of non-disclosure among untreated persons was 1.48 higher than those on treatment.
Results:
Among PLHIV, the model-estimated sensitivity of self-reported HIV testing history ranged from 96% to 99% across surveys. The model-estimated sensitivity of self-reported awareness of HIV status varied from 91% to 97%. Non-disclosure was generally higher among men and those aged 15–24 years. Adjustments for imperfect sensitivity did not substantially influence estimates of PLHIV ever tested (difference <4%) but the proportion of PLHIV aware of their HIV-positive status was higher than the unadjusted proportion (difference <8%).
Conclusions:
Self-reported HIV testing histories in four Eastern and Southern African countries are generally robust although adjustment for non-disclosure increases estimated awareness of status. These findings can contribute to further refinements in methods for monitoring progress along the HIV testing and treatment cascade.
Date Issued
2021-03-01
Date Acceptance
2020-11-09
Citation
AIDS, 2021, 35 (3), pp.503-510
ISSN
0269-9370
Publisher
Lippincott, Williams & Wilkins
Start Page
503
End Page
510
Journal / Book Title
AIDS
Volume
35
Issue
3
Copyright Statement
© 2020 Wolters Kluwer Health, Inc.
Sponsor
UNAIDS
Bill & Melinda Gates Foundation
Medical Research Council (MRC)
Identifier
https://journals.lww.com/aidsonline/Fulltext/2021/03010/Accuracy_of_self_reported_HIV_testing_history_and.17.aspx
Grant Number
2017/778519
OPP1190661
MR/R015600/1
Subjects
06 Biological Sciences
11 Medical and Health Sciences
17 Psychology and Cognitive Sciences
Virology
Publication Status
Published
Date Publish Online
2020-11-26