Chemical Engineering’s Discovery Laboratory at Imperial College London is a practical teaching programme designed specifically to support student-centred learning at an advanced level, bridging the gap between instructions driven lab experiments and fully open ended research. In the first part of this article we present an overview of this programme with particular attention given to the design of the pedagogical framework and the execution of teaching. The teaching goal is delivered by in-depth experiential learning, where students are assigned a specific subject area to conduct their own research within a set timeframe and boundary conditions that guarantee a successful learning outcome. Academic supervisors and teaching assistants play an important role in this process, where they provide students with continuing guidance throughout. The use of research or industrial grade equipment ensures the students’ preparation for their final year research project as well as their post-graduation careers. In addition to summative assessments, students also receive formative feedback periodically from academic supervisors and teaching assistants. The Discovery Laboratory has received positive feedback from both teachers and students since its inauguration in 2011 and here we share some useful insights for the execution of such a practical teaching programme.