Structure and function of the ventricular tachycardia isthmus
File(s)
Published version
Author(s)
Type
Journal Article
Abstract
Catheter ablation of postinfarction reentrant ventricular tachycardia (VT) has received renewed interest owing to the increased availability of high-resolution electroanatomic mapping systems that can describe the VT circuits in greater detail and the emergence and need to target noninvasive external beam radioablation. These recent advancements provide optimism for improving the clinical outcome of VT ablation in patients with postinfarction and potentially other scar-related VTs. The combination of analyses gleaned from studies in swine and canine models of postinfarction reentrant VT, and in human studies, suggests the existence of common electroanatomic properties for reentrant VT circuits. Characterizing these properties may be useful for increasing the specificity of substrate mapping techniques and for noninvasive identification to guide ablation. Herein, we describe properties of reentrant VT circuits that may assist in elucidating the mechanisms of onset and maintenance, as well as a means to localize and delineate optimal catheter ablation targets.
Date Issued
2022-01-01
Date Acceptance
2021-08-01
Citation
Heart Rhythm, 2022, 19 (1), pp.137-153
ISSN
1547-5271
Publisher
Elsevier
Start Page
137
End Page
153
Journal / Book Title
Heart Rhythm
Volume
19
Issue
1
Copyright Statement
©2021 Heart Rhythm Society. This isan open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/34371192
PII: S1547-5271(21)01999-8
Subjects
Catheter ablation
Isthmus
Mapping
Reentrant circuit
Ventricular tachycardia
Publication Status
Published
Coverage Spatial
United States
Date Publish Online
2021-08-06