Temporal trend analysis of rheumatic heart disease burden in high-income countries between 1990 and 2019
File(s)Accepted Manuscript.pdf (2.47 MB)
Accepted version
Author(s)
Ojha, Utkarsh
Marshall, Dominic C
Salciccioli, Justin D
Al-Khayatt, Becker M
Hammond-Haley, Matthew
Type
Journal Article
Abstract
AIMS: To assesses trends in rheumatic heart disease (RHD) burden in high-income, European Union 15+ (EU15+) countries between 1990 and 2019. METHODS AND RESULTS: Cross-sectional analysis of the incidence and mortality of RHD was conducted using data from the Global Burden of Disease Study (GBD) database. Age-standardized incidence rates (ASIRs) and age-standardized mortality rates (ASMRs) were extracted for EU15 + countries per sex for each of the years from 1990-2019, inclusive, and mortality-to-incidence indices (MII) were computed. Joinpoint regression analysis was used for the description of trends. Over 29 years, an overall declining trend in RHD incidence and mortality across EU 15 + nations were observed. There was significant variability in RHD incidence and mortality rates across high-income countries. However, both RHD incidence and mortality were higher among females compared to males across EU15 + countries over the observed period. The most recent incidence trend, starting predominantly after 2014, demonstrated a rise in RHD incidence in most countries for both sexes. The timing of this RHD resurgence corresponds temporally with an influx of migrants and refugees into Europe. The recent increasing RHD incidence rates ranged from + 0.4% to + 24.7% for males, and + 0.6% to + 11.4% for females. CONCLUSIONS: More than half of EU15 + nations display a recent increase in RHD incidence rate across both sexes. Possible factors associated with this rise are discussed and include increase in global migration from nations with higher RHD prevalence, host nation factors such as migrants' housing conditions, healthcare access and migrant health status on arrival.
Date Issued
2024-03-01
Date Acceptance
2022-12-01
Citation
European Heart Journal - Quality of Care and Clinical Outcomes, 2024, 10 (2), pp.108-120
ISSN
2058-5225
Publisher
Oxford University Press
Start Page
108
End Page
120
Journal / Book Title
European Heart Journal - Quality of Care and Clinical Outcomes
Volume
10
Issue
2
Copyright Statement
© The Author(s) 2022. Published by Oxford University Press on behalf of the European Society of Cardiology.
This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model). This is a pre-copy-editing, author-produced version of an article accepted for publication in European Heart Journal - Quality of Care and Clinical Outcomes following peer review. The definitive publisher-authenticated version Utkarsh Ojha, Dominic C Marshall, Justin D Salciccioli, Becker M Al-Khayatt, Matthew Hammond-Haley, Richard Goodall, Kim L Borsky, Conor P Crowley, Joseph Shalhoub, Adam Hartley, Temporal trend analysis of rheumatic heart disease burden in high-income countries between 1990 and 2019, European Heart Journal - Quality of Care and Clinical Outcomes, 2022;, qcac083, https://doi.org/10.1093/ehjqcco/qcac083
This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model). This is a pre-copy-editing, author-produced version of an article accepted for publication in European Heart Journal - Quality of Care and Clinical Outcomes following peer review. The definitive publisher-authenticated version Utkarsh Ojha, Dominic C Marshall, Justin D Salciccioli, Becker M Al-Khayatt, Matthew Hammond-Haley, Richard Goodall, Kim L Borsky, Conor P Crowley, Joseph Shalhoub, Adam Hartley, Temporal trend analysis of rheumatic heart disease burden in high-income countries between 1990 and 2019, European Heart Journal - Quality of Care and Clinical Outcomes, 2022;, qcac083, https://doi.org/10.1093/ehjqcco/qcac083
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/36477873
PII: 6881717
Subjects
Global Burden of Disease
Incidence
Mortality
Rheumatic heart disease
Trends
Publication Status
Published
Coverage Spatial
England
Date Publish Online
2022-12-07