Identifying barriers to idiopathic pulmonary fibrosis treatment: a survey of patient and physician views
File(s)
Author(s)
Type
Journal Article
Abstract
BACKGROUND: Antifibrotics are recommended for the treatment of individuals with idiopathic pulmonary fibrosis (IPF), but treatment use remains at ∼60%. OBJECTIVE: To investigate the views of individuals with IPF and pulmonologists on the diagnosis and management of IPF to understand treatment patterns. METHODS: Interviews and/or online surveys were completed by patients and pulmonologists from Canada, France, Germany, Italy, Spain, and the UK. Responses from physicians were analyzed by time between diagnosis and treatment initiation in the majority of patients with IPF (group A, > 4 months; group B, ≤4 months). Statistical comparisons between physicians were undertaken using z tests, with p < 0.05 considered statistically significant. RESULTS: The physicians in group A saw fewer patients, were less comfortable discussing the IPF prognosis with patients, and had less belief in the benefits of antifibrotic treatments than the physicians in group B. These physicians' attitudes contrasted with those of the patients, who wanted more information about the IPF prognosis and pharmacological treatment options at diagnosis and were more concerned about preventing disease progression than avoiding medication side effects. Differences between countries were found regarding physicians' comfort in discussing the prognosis at diagnosis and access to care. CONCLUSIONS: Several barriers to antifibrotic treatment, principally reflecting the differing views and values of patients and physicians, were identified in this study, suggesting a need for better patient-physician communication about pharmacological therapy for IPF.
Date Issued
2018-08-16
Date Acceptance
2018-06-05
Citation
Respiration, 2018, 96 (6), pp.514-524
ISSN
1423-0356
Publisher
Karger Publishers
Start Page
514
End Page
524
Journal / Book Title
Respiration
Volume
96
Issue
6
Copyright Statement
© 2018 S. Karger AG, Basel.
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/30114692
PII: 000490667
Subjects
Antifibrotic treatment
Barriers to treatment
Idiopathic pulmonary fibrosis
Patient-physician communication
Publication Status
Published online
Coverage Spatial
Switzerland
Date Publish Online
2018-08-16