Masked crystalline light chain tubulopathy and podocytopathy with focal segmental glomerulosclerosis: a rare MGRS-associated renal lesion
File(s)
Accepted version
Author(s)
Type
Journal Article
Abstract
Monoclonal Gammopathy of Renal Significance (MGRS) encompasses a wide spectrum of histopathology. Characterizing rare forms of MGRS-related renal pathology remains work in progress. Light chain crystalline podocytopathy in the context of MGRS, either in isolation or combined with proximal tubulopathy (LCPT) has rarely been described. Unravelling MGRS pathologies is critical for patient management and often requires ancillary techniques for antigen retrieval to demonstrate light chain (LC) restriction on immunofluorescence (IF).
Date Issued
2021-08-01
Date Acceptance
2021-03-04
Citation
Histopathology, 2021, 79 (2), pp.265-268
ISSN
1365-2559
Start Page
265
End Page
268
Journal / Book Title
Histopathology
Volume
79
Issue
2
Copyright Statement
This article is protected by copyright. All rights reserved.
Sponsor
Imperial College Healthcare NHS Trust- BRC Funding
Imperial College Healthcare NHS Trust
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/33666277
Grant Number
RDA28
FR410
Subjects
Monoclonal gammopathy of renal significance
focal segmental glomerulosclerosis
light chain tubulopathy
podocytopathy
Publication Status
Published
Coverage Spatial
England
Date Publish Online
2021-03-05