Genomic epidemiology of severe acute respiratory syndrome Coronavirus 2, Colombia
File(s)
Author(s)
Laiton-Donato, Katherine
Julian Villabona-Arenas, Christian
Usme-Ciro, Jose A
Franco-Munoz, Carlos
Alvarez-Diaz, Diego A
Type
Journal Article
Abstract
Coronavirus disease (COVID-19) in Colombia was first diagnosed in a traveler arriving from Italy on February 26, 2020. However, limited data are available on the origins and number of introductions of COVID-19 into the country. We sequenced the causative agent of COVID-19, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), from 43 clinical samples we collected, along with another 79 genome sequences available from Colombia. We investigated the emergence and importation routes for SARS-CoV-2 into Colombia by using epidemiologic, historical air travel, and phylogenetic observations. Our study provides evidence of multiple introductions, mostly from Europe, and documents >12 lineages. Phylogenetic findings validate the lineage diversity, support multiple importation events, and demonstrate the evolutionary relationship of epidemiologically linked transmission chains. Our results reconstruct the early evolutionary history of SARS-CoV-2 in Colombia and highlight the advantages of genome sequencing to complement COVID-19 outbreak investigations.
Date Issued
2020-12-01
Date Acceptance
2020-09-01
Citation
Emerging Infectious Diseases, 2020, 26 (12), pp.2854-2862
ISSN
1080-6040
Publisher
U.S. National Center for Infectious Diseases
Start Page
2854
End Page
2862
Journal / Book Title
Emerging Infectious Diseases
Volume
26
Issue
12
Copyright Statement
All materials published in Emerging Infectious Diseases, including text, figures, tables, and photographs, are in the public domain and can be reprinted or used without permission with proper citation. All content is freely available without charge to the user or his/her institution. In accordance with the Budapest Open Access InitiativeExternal Link definition of open access, users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. Because the journal is in the public domain, its usage policy also conforms to conditions set forth by Creative Commons Licence.
License URL
Sponsor
Medical Research Council (MRC)
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000609133900007&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Grant Number
MR/R015600/1
Subjects
Science & Technology
Life Sciences & Biomedicine
Immunology
Infectious Diseases
ALIGNMENT
Publication Status
Published