Permanent bilateral carotid filters for stroke prevention in atrial fibrillation.
File(s)Current Opinion.pdf (2.61 MB)
Published version
Author(s)
Type
Journal Article
Abstract
PURPOSE OF REVIEW: A novel permanent carotid filter device for percutaneous implantation was developed for the purpose of stroke prevention. In this review, we cover rationale, existing preclinical and clinical data, and potential future directions for research using such a device. RECENT FINDINGS: The Vine™ filter was assessed for safety in sheep and in 2 observational human studies, the completed CAPTURE 1 (n = 25) and the ongoing CAPTURE 2 (planned n = 100). CAPTURE 1 has shown high procedural and long-term implant safety. A control group was not available for comparison. A mechanical filter for permanent stroke prevention can be implanted bilaterally in the common carotid artery safely and efficiently. A randomized trial is planned for 2021 (n = 3500, INTERCEPT) to demonstrate superiority of a filter + anticoagulation strategy over anticoagulation alone in patients at high risk for ischemic stroke.
Date Issued
2020-09-10
Date Acceptance
2020-09-01
Citation
Current Cardiology Reports, 2020, 22 (11), pp.144-144
ISSN
1523-3782
Publisher
Springer
Start Page
144
End Page
144
Journal / Book Title
Current Cardiology Reports
Volume
22
Issue
11
Copyright Statement
© The Author(s) 2020. This article is licensed under a Creative Commons
Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as
you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were
made. The images or other third party material in this article are included
in the article's Creative Commons licence, unless indicated otherwise in a
credit line to the material. If material is not included in the article's
Creative Commons licence and your intended use is not permitted by
statutory regulation or exceeds the permitted use, you will need to obtain
permission directly from the copyright holder. To view a copy of this
licence, visit http://creativecommons.org/licenses/by/4.0/.
Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as
you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were
made. The images or other third party material in this article are included
in the article's Creative Commons licence, unless indicated otherwise in a
credit line to the material. If material is not included in the article's
Creative Commons licence and your intended use is not permitted by
statutory regulation or exceeds the permitted use, you will need to obtain
permission directly from the copyright holder. To view a copy of this
licence, visit http://creativecommons.org/licenses/by/4.0/.
License URL
Sponsor
St Marys Development Trust
Commission of the European Communities
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/32910288
PII: 10.1007/s11886-020-01388-w
Grant Number
RE:SOBELL CHAIR
754517
Subjects
Atrial fibrillation
Carotid filter
Common carotid artery
Embolic protection
Stroke prevention
Publication Status
Published online
Coverage Spatial
United States
Date Publish Online
2020-09-10