Parkinson's disease treatments: focus on transcranial direct current stimulation (tDCS)
File(s)
Author(s)
Tahtis, V
Kaski, D
Type
Journal Article
Abstract
Parkinson’s disease (PD) is among the most common progressive neurodegenerative conditions worldwide, characterized by bradykinesia, rigidity, tremor, and postural instability, in addition to a variety of cognitive and behavior complications. Current pharmacological treatment options focus on dopaminergic replacement, but these become less efficacious as the disease progresses. Noninvasive brain stimulation techniques have therefore gained favor in recent years as a means of treating the motor and non-motor complications of PD. Here we review the evidence behind the use of transcranial direct current stimulation in the treatment of motor and non-motor complications of PD, discuss the limitations that have hindered the introduction of transcranial direct current stimulation into mainstream clinical practice, and highlight future directions that may enable the translation of this research tool into clinical use.
Date Issued
2017-10-16
Date Acceptance
2017-09-23
Citation
Journal of Parkinsonism and Restless Legs Syndrome, 2017, 7, pp.55-70
ISSN
1927-7733
Publisher
Dove Medical Press
Start Page
55
End Page
70
Journal / Book Title
Journal of Parkinsonism and Restless Legs Syndrome
Volume
7
Copyright Statement
© 2017 Tahtis and Kaski. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.
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you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For
permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work
you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For
permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000413032400001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Subjects
Science & Technology
Life Sciences & Biomedicine
Clinical Neurology
Neurosciences & Neurology
Parkinson's disease
transcranial direct current stimulation
motor
cognitive
non-motor
NONINVASIVE CORTICAL STIMULATION
DORSOLATERAL PREFRONTAL CORTEX
LEVODOPA-INDUCED DYSKINESIAS
MILD COGNITIVE IMPAIRMENT
PRIMARY MOTOR CORTEX
MAGNETIC STIMULATION
WORKING-MEMORY
FUNCTIONAL MOBILITY
BRAIN-STIMULATION
MAJOR DEPRESSION
Publication Status
Published