Proof of concept of a novel neck-situated wearable PPG system for continuous physiological monitoring
OA Location
Author(s)
Singh, Sukhpreet
Kozlowski, Michal
Garcia-Lopez, Irene
Jiang, Zhou
Rodriguez-Villegas, Esther
Type
Journal Article
Abstract
Continuous overnight vital signs monitoring would be ideal for patients suffering from epilepsy, where life-threatening hypoxemias can occur during sleep. However, the existing physiological monitoring systems suffer from limitations in terms of usability factors and/or limited information of the signals being acquired. The body location of the monitoring system is a crucial consideration, seldom addressed by the wider community. This article presents a proof-of-concept, neck-worn photoplethysmography system, which was developed and tested to assess the feasibility of the neck as a monitoring site for longitudinal sensing of cardiac and respiratory responses during sleep. The novel system was compared against a gold-standard commercial multichannel cardiorespiratory polysomnography (PSG) system during oxygen desaturation cycles, to assess its ability to measure heart rate, respiratory rate (RR), and peripheral blood oxygen saturation (SpO 2 ) on 15 participants. The findings for heart rate showed a marginal mean error of 0.47 beats/min with limits of agreement (LOA) at 95% confidence between −3.17 and 4 bpm. RR comparisons had an overall mean error of 0.43 breaths/min, with LOA at 95% confidence between −2.73 and 3.3 bpm. Lastly, the system accurately outputs SpO 2 with an overall root-mean-square error of 1.44% between 90 and 100% SpO 2 using a custom calibration method. Moreover, it was observed that the neck made it possible for the system to detect desaturation events on an average 12.6 s prior to the PSG system, which used a peripheral finger-based PPG system. Ultimately, this proof-of-concept study illustrates the viability of neck-based sensing for minimally invasive monitoring of cardiac and respiratory vitals during sleep.
Date Issued
2021-05-26
Date Acceptance
2021-04-26
Citation
IEEE Transactions on Instrumentation and Measurement, 2021, 70, pp.1-9
ISSN
0018-9456
Publisher
Institute of Electrical and Electronics Engineers
Start Page
1
End Page
9
Journal / Book Title
IEEE Transactions on Instrumentation and Measurement
Volume
70
Copyright Statement
© 2021 The Author(s). This work is licensed under a Creative Commons Attribution 4.0 License. For more information, see https://creativecommons.org/licenses/by/4.0/
License URL
Sponsor
Commission of the European Communities
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000693605100011&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Grant Number
724334
Subjects
Science & Technology
Technology
Engineering, Electrical & Electronic
Instruments & Instrumentation
Engineering
Biomedical monitoring
epilepsy
photoplethysmography (PPG)
pulse oximetry
wearable sensors
SUDDEN UNEXPECTED DEATH
EPILEPSY
MECHANISMS
SEIZURES
RISK
Publication Status
Published
Article Number
ARTN 9509609
Date Publish Online
2021-05-26