Repository logo
  • Log In
    Log in via Symplectic to deposit your publication(s).
Repository logo
  • Communities & Collections
  • Research Outputs
  • Statistics
  • Log In
    Log in via Symplectic to deposit your publication(s).
  1. Home
  2. Faculty of Medicine
  3. National Heart and Lung Institute
  4. Airway Disease
  5. How can we minimise the use of regular oral corticosteroids in asthma?
 
  • Details
How can we minimise the use of regular oral corticosteroids in asthma?
File(s)
How can we minimise the use of regular oral corticosteroids in asthma.pdf (606.59 KB)
Published version
Author(s)
Bourdin, Arnaud
Adcock, Ian
Berger, Patrick
Bonniaud, Philippe
Chanson, Philippe
more
Type
Journal Article
Abstract
Options to achieve oral corticosteroid (OCS)-sparing have been triggering increasing interest since the 1970s because of the side-effects of OCSs, and this has now become achievable with biologics. The Société de Pneumologie de Langue Française workshop on OCSs aimed to conduct a comprehensive review of the basics for OCS use in asthma and issue key research questions. Pharmacology and definition of regular use were reviewed by the first working group (WG1). WG2 examined whether regular OCS use is associated with T2 endotype. WG3 reported on the specificities of the paediatric area. Key "research statement proposals" were suggested by WG4. It was found that the benefits of regular OCS use in asthma outside episodes of exacerbations are poorly supported by the existing evidence. However, complete OCS elimination couldn't be achieved in any available studies for all patients and the panel felt that it was too early to conclude that regular OCS use could be declared criminal. Repeated or prolonged need for OCS beyond 1 g·year-1 should indicate the need for referral to secondary/tertiary care. A strategic sequential plan aiming at reducing overall exposure to OCS in severe asthma was then held as a conclusion of the workshop.
Date Issued
2020-03-31
Date Acceptance
2019-11-04
Citation
European Respiratory Review, 2020, 29 (155)
URI
http://hdl.handle.net/10044/1/76705
DOI
https://www.dx.doi.org/10.1183/16000617.0085-2019
ISSN
0905-9180
Publisher
European Respiratory Society
Journal / Book Title
European Respiratory Review
Volume
29
Issue
155
Copyright Statement
©ERS 2020. http://creativecommons.org/licenses/by-nc/4.0/This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0 (https://creativecommons.org/licenses/by-nc/4.0/)
License URL
https://creativecommons.org/licenses/by-nc/4.0/
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/32024721
PII: 29/155/190085
Publication Status
Published
Coverage Spatial
England
Date Publish Online
2020-02-05
About
Spiral Depositing with Spiral Publishing with Spiral Symplectic
Contact us
Open access team Report an issue
Other Services
Scholarly Communications Library Services
logo

Imperial College London

South Kensington Campus

London SW7 2AZ, UK

tel: +44 (0)20 7589 5111

Accessibility Modern slavery statement Cookie Policy

Built with DSpace-CRIS software - Extension maintained and optimized by 4Science

  • Cookie settings
  • Privacy policy
  • End User Agreement
  • Send Feedback