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Assessing a sustainable manufacturing route to lapatinib
File(s)
d2re00267a.pdf (397.4 KB)
Published version
Author(s)
Stark, Roderick T
Pye, Dominic
Chen, Wenyi
Newton, Oliver J
Deadman, Benjamin J
Type
Journal Article
Abstract
A synthetic route to an anti-cancer drug, lapatinib, was devised to support the development of a sustainable manufacturing process in South Africa. Quantitative metrics were employed to evaluate the sustainability of the key steps of the reaction.
Date Issued
2022-08-09
Date Acceptance
2022-08-05
Citation
Reaction Chemistry and Engineering, 2022, 7 (11), pp.2420-2426
URI
URL
DOI
ISSN
2058-9883
Publisher
Royal Society of Chemistry
Start Page
2420
End Page
2426
Journal / Book Title
Reaction Chemistry and Engineering
Volume
7
Issue
11
Copyright Statement
© The Royal Society of Chemistry 2022. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
License URL
Identifier
https://pubs.rsc.org/en/content/articlelanding/2022/RE/D2RE00267A
Subjects
Science & Technology
Physical Sciences
Technology
Chemistry, Multidisciplinary
Engineering, Chemical
Chemistry
Engineering
INHIBITORS
EGFR
Publication Status
Published
Date Publish Online
2022-08-09