Self-reported symptoms of chronic cough and breathlessness in working-age men in the city of Izhevsk, Russia: Associations with cardiovascular disease risk factors and co-morbidities
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Author(s)
Cook, S
Quint, JK
Vasiljev, M
Leon, DA
Type
Journal Article
Abstract
Introduction: Very little is known about the prevalence of respiratory symptoms or their associations with other health conditions in Russia.
Methods: Between 2008-10 a sample of 983 men resident in Izhevsk, Russia took part in a cross-sectional survey. Presence of respiratory symptoms was determined from self-report of chronic productive cough and breathlessness assessed using the British Medical Research Council breathlessness scale. Self-reported physical and mental health were measured using the SF-12. Hypertension was assessed from mean blood pressure measured at the health check and/or self-reported use of anti-hypertensive medication. Other co-morbidities were assessed from self-report. Logistic regression models were fitted assessing the association between respiratory symptoms and co-morbidities. Linear regression models were fitted to investigate the association between respiratory symptoms and self-reported health scores. All models were adjusted for age, education, and smoking status.
Results: The age standardized prevalence of cough and breathlessness was 20.9% (prevalence with breathlessness MRC grade 3 or above 3.7%). The majority of men with respiratory symptoms (87.3%) were current smokers. Cough and breathlessness was associated with substantially worse self-reported physical and mental health (test for tend with severity of breathlessness p<0.001). Those with chronic cough and grade 3 or above breathlessness had higher odds of having hypertension (OR 3.03 95% CI 1.36, 6.74), diabetes (OR 10.55 (95% CI 2.69, 41.37), angina pectoris (OR 7.54 95% CI 3.61, 15.73), previous myocardial infarction (OR 7.61 95% CI 2.10, 27.4) and previous stroke (OR 6.61 95% CI 1.75, 23.34) compared to those without respiratory symptoms.
Conclusions: The prevalence of respiratory symptoms was high. Strong associations were found between respiratory symptoms and cardiovascular co-morbidities. These are of particular importance given the extremely high level of cardiovascular disease mortality in Russia.
Methods: Between 2008-10 a sample of 983 men resident in Izhevsk, Russia took part in a cross-sectional survey. Presence of respiratory symptoms was determined from self-report of chronic productive cough and breathlessness assessed using the British Medical Research Council breathlessness scale. Self-reported physical and mental health were measured using the SF-12. Hypertension was assessed from mean blood pressure measured at the health check and/or self-reported use of anti-hypertensive medication. Other co-morbidities were assessed from self-report. Logistic regression models were fitted assessing the association between respiratory symptoms and co-morbidities. Linear regression models were fitted to investigate the association between respiratory symptoms and self-reported health scores. All models were adjusted for age, education, and smoking status.
Results: The age standardized prevalence of cough and breathlessness was 20.9% (prevalence with breathlessness MRC grade 3 or above 3.7%). The majority of men with respiratory symptoms (87.3%) were current smokers. Cough and breathlessness was associated with substantially worse self-reported physical and mental health (test for tend with severity of breathlessness p<0.001). Those with chronic cough and grade 3 or above breathlessness had higher odds of having hypertension (OR 3.03 95% CI 1.36, 6.74), diabetes (OR 10.55 (95% CI 2.69, 41.37), angina pectoris (OR 7.54 95% CI 3.61, 15.73), previous myocardial infarction (OR 7.61 95% CI 2.10, 27.4) and previous stroke (OR 6.61 95% CI 1.75, 23.34) compared to those without respiratory symptoms.
Conclusions: The prevalence of respiratory symptoms was high. Strong associations were found between respiratory symptoms and cardiovascular co-morbidities. These are of particular importance given the extremely high level of cardiovascular disease mortality in Russia.
Date Issued
2015-12-23
Date Acceptance
2015-10-20
Citation
BMJ Open Respiratory Research, 2015, 2
ISSN
2052-4439
Publisher
BMJ Publishing Group
Journal / Book Title
BMJ Open Respiratory Research
Volume
2
Copyright Statement
© 2015, British Medical Journal Publishing Group. This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://
creativecommons.org/licenses/by/4.0/
creativecommons.org/licenses/by/4.0/
License URL
Subjects
COPD epidemiology
Clinical Epidemiology
Publication Status
Published
Article Number
e000104