An Automated Algorithm for Determining Conduction Velocity, Wavefront Direction and Focal Source Location using a Multipolar Catheter
File(s)ConductionVelocityPaperv4.pdf (1.13 MB)
Accepted version
Author(s)
Type
Conference Paper
Abstract
Determining locations of focal arrhythmia sources and quantifying myocardial conduction velocity (CV) are two major challenges in clinical catheter ablation cases. CV, wavefront direction and focal source location can be estimated from multipolar catheter data, but currently available methods are time-consuming, limited to specific electrode configurations, and can be inaccurate. We developed automated algorithms to rapidly identify CV from multipolar catheter data with any arrangement of electrodes, whilst providing estimates of wavefront direction and focal source position, which can guide the catheter towards a focal arrhythmic source. We validated our methods using simulations on realistic human left atrial geometry. We subsequently applied them to clinically-acquired intracardiac electrogram data, where CV and wavefront direction were accurately determined in all cases, whilst focal source locations were correctly identified in 2/3 cases. Our novel automated algorithms can potentially be used to guide ablation of focal arrhythmias in real-time in cardiac catheter laboratories.
Date Issued
2014-08-26
Citation
2014
Copyright Statement
© 2014 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Description
28.07.15 KB. Ok to add accepted version to spiral
Source
IEEE Engineering in Medicine and Biology Conference
Start Date
2014-08-26
Finish Date
2014-08-30
Coverage Spatial
Chicago