Perinatal paracetamol exposure in mice does not affect the development of allergic airways disease in early life.
File(s)Thorax-2015-Lee.pdf (720.53 KB)
Published version
Author(s)
Type
Journal Article
Abstract
Current data concerning maternal paracetamol intake during pregnancy, or intake during infancy and risk of wheezing or asthma in childhood is inconclusive based on epidemiological studies. We have investigated whether there is a causal link between maternal paracetamol intake during pregnancy and lactation and the development of house dust mite (HDM) induced allergic airways disease (AAD) in offspring using a neonatal mouse model.
Date Issued
2015-04-03
Date Acceptance
2015-02-24
Citation
Thorax, 2015
ISSN
1468-3296
Publisher
BMJ Publishing Group Ltd
Journal / Book Title
Thorax
Copyright Statement
© 2015 the Authors. This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/
License URL
Identifier
http://www.ncbi.nlm.nih.gov/pubmed/25841236
PII: thoraxjnl-2014-205280
Subjects
Allergic lung disease
Asthma
Paediatric asthma