The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss
File(s)
Published version
Author(s)
Ruban, Aruchuna
Ashrafian, Hutan
Teare, Julian P
Type
Journal Article
Abstract
The rapid rise of obesity and type 2 diabetes poses a global threat to healthcare and is a major cause of mortality and morbidity. Bariatric surgery has revolutionised the treatment of both these conditions but is invasive and associated with an increased risk of complications. The EndoBarrier is a device placed endoscopically in the duodenum, which is designed to mimic the effects of gastric bypass surgery with the aim of inducing weight loss and improving glycaemic control. This review outlines the current clinical evidence of the device, its efficacy, potential mechanisms of action, and utility in clinical practice.
Date Issued
2018-07-26
Date Acceptance
2018-07-12
Citation
GASTROENTEROLOGY RESEARCH AND PRACTICE, 2018, 2018
ISSN
1687-6121
Publisher
HINDAWI LTD
Journal / Book Title
GASTROENTEROLOGY RESEARCH AND PRACTICE
Volume
2018
Copyright Statement
© 2018 Aruchuna Ruban et al. This is an open access article distributed under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Sponsor
National Institute for Health Research
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000440921400001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Grant Number
12/10/04
Subjects
Science & Technology
Life Sciences & Biomedicine
Gastroenterology & Hepatology
HUMAN GUT MICROBIOTA
Y GASTRIC BYPASS
BARIATRIC SURGERY
GLYCEMIC CONTROL
BILE-ACIDS
OBESITY
GLUCOSE
MULTICENTER
METABOLISM
EFFICACY
Publication Status
Published
Article Number
ARTN 7823182
Date Publish Online
2018-07-26