Finger-actuated microneedle array for sampling body fluids
File(s)
Author(s)
Sarabi, Misagh Rezapour
Ahmadpour, Abdollah
Yetisen, Ali K
Tasoglu, Savas
Type
Journal Article
Abstract
The application of microneedles (MNs) for minimally invasive biological fluid sampling is rapidly emerging, offering a user-friendly approach with decreased insertion pain and less harm to the tissues compared to conventional needles. Here, a finger-powered microneedle array (MNA) integrated with a microfluidic chip was conceptualized to extract body fluid samples. Actuated by finger pressure, the microfluidic device enables an efficient approach for the user to collect their own body fluids in a simple and fast manner without the requirement for a healthcare worker. The processes for extracting human blood and interstitial fluid (ISF) from the body and the flow across the device, estimating the amount of the extracted fluid, were simulated. The design in this work can be utilized for the minimally invasive personalized medical equipment offering a simple usage procedure
Date Issued
2021-06-01
Date Acceptance
2021-06-01
Citation
Applied Sciences-Basel, 2021, 11 (12)
ISSN
2076-3417
Publisher
MDPI AG
Journal / Book Title
Applied Sciences-Basel
Volume
11
Issue
12
Copyright Statement
: © 2021 by the authors.
Licensee MDPI, Basel, Switzerland.
This article is an open access article
distributed under the terms and
conditions of the Creative Commons
Attribution (CC BY) license (https://
creativecommons.org/licenses/by/
4.0/).
Licensee MDPI, Basel, Switzerland.
This article is an open access article
distributed under the terms and
conditions of the Creative Commons
Attribution (CC BY) license (https://
creativecommons.org/licenses/by/
4.0/).
License URL
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000666073500001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Subjects
Science & Technology
Physical Sciences
Technology
Chemistry, Multidisciplinary
Engineering, Multidisciplinary
Materials Science, Multidisciplinary
Physics, Applied
Chemistry
Engineering
Materials Science
Physics
microneedles
microfluidics
finite-element method
fluid mechanics
wearables
INTERSTITIAL FLUID
HOLLOW MICRONEEDLE
SKIN PENETRATION
BLOOD-FLOW
LOW-COST
FABRICATION
PATCH
EXTRACTION
DEVICES
SYSTEMS
Publication Status
Published
Article Number
ARTN 5329
Date Publish Online
2021-06-08