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In vitro susceptibility to closthioamide among clinical and reference strains of Neisseria gonorrhoeae
File(s)
Author(s)
Miari, VF
Solanki, P
Hleba, Y
Stabler, RA
Heap, JT
Type
Journal Article
Abstract
Neisseria gonorrhoeae is one of the leading antimicrobial resistance threats worldwide. This study determined the minimum inhibitory concentrations of closthioamide to be 0.008-0.5 mg/L for clinical N. gonorrhoeae strains and related species. Cross-resistance with existing antimicrobial resistance was not detected, indicating that closthioamide could be used to treat drug-resistant N. gonorrhoeae.
Date Issued
2017-08-07
Date Acceptance
2017-07-26
Citation
Antimicrobial Agents and Chemotherapy, 2017, 10 (10)
URI
DOI
ISSN
0066-4804
Publisher
American Society for Microbiology
Journal / Book Title
Antimicrobial Agents and Chemotherapy
Volume
10
Issue
10
Copyright Statement
Copyright © 2017 Miari et al.
This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
License URL
Sponsor
Biotechnology and Biological Sciences Research Council (BBSRC)
Grant Number
BB/M002454/1
Subjects
Neisseria gonorrhoeae
antimicrobial agents
closthioamide
0605 Microbiology
1108 Medical Microbiology
1115 Pharmacology And Pharmaceutical Sciences
Microbiology
Article Number
e00929-17