Selenium saves ferroptotic TFH cells to fortify the germinal center
File(s)Linterman_N&V_revised.docx (1.13 MB)
Accepted version
Author(s)
Linterman, Michelle A
Denton, Alice E
Type
Journal Article
Abstract
Inhibition of ferroptosis via selenium supplementation promotes the survival of follicular helper T cells, boosting the germinal center and antibody response following vaccination in mice and people.
Date Issued
2021-09-01
Date Acceptance
2021-08-01
Citation
Nature Immunology, 2021, 22, pp.1074-1076
ISSN
1529-2908
Publisher
Springer Science and Business Media LLC
Start Page
1074
End Page
1076
Journal / Book Title
Nature Immunology
Volume
22
Copyright Statement
© 2021, Springer Nature America, Inc.
Sponsor
Medical Research Council (MRC)
Identifier
https://www.nature.com/articles/s41590-021-01007-y
Grant Number
MR/V009591/1
Subjects
Science & Technology
Life Sciences & Biomedicine
Immunology
IMMUNITY
Germinal Center
Selenium
T-Lymphocytes, Helper-Inducer
Germinal Center
T-Lymphocytes, Helper-Inducer
Selenium
1107 Immunology
Immunology
Publication Status
Published
Date Publish Online
2021-08-19