Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappa B suppression

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Author(s)

Ito, K

Yamamura, S

Essilfie-Quaye, S

Cosio, B

Ito, M

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Type

Journal Article

Date Issued

2006-01-23

Date Acceptance

2005-11-21

Citation

Journal of Experimental Medicine, 2006, 203 (1), pp.7-13

URI

http://hdl.handle.net/10044/1/31759

DOI

https://www.dx.doi.org/10.1084/jem.20050466

ISSN

1540-9538

Publisher

Rockefeller University Press

Start Page

7

End Page

13

Journal / Book Title

Journal of Experimental Medicine

Volume

203

Issue

1

Copyright Statement

© 2006 Rockefeller University Press

Sponsor

Medical Research Council (MRC)

Grant Number

G0401662

Subjects

Science & Technology

Life Sciences & Biomedicine

Immunology

Medicine, Research & Experimental

Research & Experimental Medicine

IMMUNOLOGY

MEDICINE, RESEARCH & EXPERIMENTAL

OBSTRUCTIVE PULMONARY-DISEASE

ALVEOLAR MACROPHAGES

GENE-EXPRESSION

ESTROGEN-RECEPTOR

ACETYLATION

REPRESSION

DEXAMETHASONE

INHIBITION

ASTHMA

CELLS

Cell Line, Tumor

Cells, Cultured

Dexamethasone

Gene Expression Regulation, Enzymologic

Granulocyte-Macrophage Colony-Stimulating Factor

Histone Deacetylase 2

Histone Deacetylases

Humans

Interleukin-1

Macrophages, Alveolar

NF-kappa B

Pulmonary Disease, Chronic Obstructive

RNA, Small Interfering

Receptors, Glucocorticoid

Repressor Proteins

Transcriptional Activation

Transfection

11 Medical And Health Sciences

Publication Status

Published