Discriminative information added by wearable sensors for early screening - a case study on diabetic peripheral neuropathy
File(s)1570522562.pdf (1.14 MB)
Accepted version
Author(s)
Type
Conference Paper
Abstract
Wearable inertial sensors have demonstrated their potential to screen for various neuropathies and neurological disorders. Most such research has been based on classification algorithms that differentiate the control group from the pathological group, using biomarkers extracted from wearable data as predictors. However, such methods often lack quantitative evaluation of how much information provided by the wearable biomarkers contributes to the overall prediction. Despite promising results from internal cross validation, their utility in clinical practice remains unclear. In this paper, we highlight in a case study - early screening for diabetic peripheral neuropathy (DPN) - evaluation methods for quantifying the contribution of wearable inertial sensors. Using a quick-to-deploy wearable sensor system, we collected 106 in-hospital diabetic patients' gait data and developed logistic regression models to predict the risk of a diabetic patient having DPN. Adopting various metrics, we evaluated the discriminative information added by gait biomarkers and how much it improved screening. The results show that the proposed wearable system added useful information significantly to the existing clinical standards, and boosted the C-index significantly from 0.75 to 0.84, surpassing the current survey-based screening methods used in clinics.
Date Issued
2019-07-25
Date Acceptance
2019-05-01
Citation
2019 IEEE 16TH INTERNATIONAL CONFERENCE ON WEARABLE AND IMPLANTABLE BODY SENSOR NETWORKS (BSN), 2019, pp.1-4
ISSN
2376-8886
Publisher
IEEE
Start Page
1
End Page
4
Journal / Book Title
2019 IEEE 16TH INTERNATIONAL CONFERENCE ON WEARABLE AND IMPLANTABLE BODY SENSOR NETWORKS (BSN)
Copyright Statement
© 2019 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Sponsor
Engineering & Physical Science Research Council (E
Engineering & Physical Science Research Council (EPSRC)
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000492872400030&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Grant Number
EP/K503733/1
EP/L014149/1
Source
IEEE 16th International Conference on Wearable and Implantable Body Sensor Networks (BSN)
Subjects
Science & Technology
Technology
Computer Science, Interdisciplinary Applications
Engineering, Electrical & Electronic
Computer Science
Engineering
Publication Status
Published
Start Date
2019-05-19
Finish Date
2019-05-22
Coverage Spatial
Univ Illinois Chicago, Chicago, IL
Date Publish Online
2019-07-25