Basal cell carcinoma (BCC) is the most common skin malignancy, and the incidence increases over time. However, epidemiological data and analysis of the histopathological characteristic of BCC in Asia and Indonesia are limited. This study evaluates the clinicopathological and histomorphological features of BCC cases at Dr. Cipto Mangunkusumo Hospital (CMH) for the last 20 years (2000-2019). This is a cross-sectional retrospective study, using medical records and slides data screened based on inclusion and exclusion criteria. The re-diagnostic assessment was performed independently by two investigators. Data were analyzed statistically by the chi-square test, Kruskal Wallis, and Mann Whitney tests. There were 896 cases of total 20 years, with an increase of 51.4% between the first and second decades, female: male ratio was 1.34: 1, the median age was 63 y.o (0-99), and 54% patient was 60-79 y.o. The majority of cases are located on the head, face, and neck (95.8%), nodular as the most common histological subtypes (49.2%), with adenoid as the highest number of variants (63.1%). Single vs mixed subtype BCC (58.4% vs 41.6%), low-risk vs high-risk BCC (53.9% vs 46.1%). There were different levels of risk and a number of subtypes based on anatomical location. The differences were also found in the number of subtypes, the aggressiveness of subtypes, and risk levels based on gender and histological subtypes based on anatomical location. Residual tumours were present in 2.8% of cases. Thus the cases of BCC in CMH have increased in the last 20 years, and differences are observed in anatomical distribution, gender, age, risk, number of subtypes, histological subtypes, and aggressiveness.