Prevalence and determinants of chronic respiratory diseases in adults in Khartoum State, Sudan
Author(s)
Type
Journal Article
Abstract
BACKGROUND: Chronic respiratory diseases (CRDs) are considered a significant cause of morbidity and mortality worldwide, although data from Africa are limited. This study aimed to determine the prevalence and determinants of CRDs in Khartoum, Sudan.
METHODS: Data were collected from 516 participants aged ≥40 years, who had completed a questionnaire and undertook pre- and post-bronchodilator spirometry testing. Trained field workers administered the questionnaires and conducted spirometry. Survey-weighted prevalence of respiratory symptoms and spirometric abnormalities were estimated. Regression analysis models were used to identify risk factors for chronic lung diseases.
RESULTS: Using the Third National Health and Nutrition Examination Survey, 1988–1994 (NHANES III) reference equations, the prevalence of chronic airflow obstruction (CAO) was 10%. The main risk factor was older age, 60–69 years (OR 3.16, 95% CI 1.20–8.31). Lower education, high body mass index and a history of TB were also identified as significant risk factors. The prevalence of a low forced vital capacity (FVC) using NHANES III was 62.7% (SE 2.2) and 11.3% (SE 1.4) using locally derived values.
CONCLUSION: The prevalence of spirometric abnormality, mainly low FVC, was high, suggesting that CRD is of substantial public health importance in urban Sudan. Strategies for the prevention and control of these problems are needed.
METHODS: Data were collected from 516 participants aged ≥40 years, who had completed a questionnaire and undertook pre- and post-bronchodilator spirometry testing. Trained field workers administered the questionnaires and conducted spirometry. Survey-weighted prevalence of respiratory symptoms and spirometric abnormalities were estimated. Regression analysis models were used to identify risk factors for chronic lung diseases.
RESULTS: Using the Third National Health and Nutrition Examination Survey, 1988–1994 (NHANES III) reference equations, the prevalence of chronic airflow obstruction (CAO) was 10%. The main risk factor was older age, 60–69 years (OR 3.16, 95% CI 1.20–8.31). Lower education, high body mass index and a history of TB were also identified as significant risk factors. The prevalence of a low forced vital capacity (FVC) using NHANES III was 62.7% (SE 2.2) and 11.3% (SE 1.4) using locally derived values.
CONCLUSION: The prevalence of spirometric abnormality, mainly low FVC, was high, suggesting that CRD is of substantial public health importance in urban Sudan. Strategies for the prevention and control of these problems are needed.
Date Issued
2023-05-01
Date Acceptance
2022-12-29
Citation
International Journal of Tuberculosis and Lung Disease, 2023, 27 (5), pp.373-380
ISSN
1027-3719
Publisher
International Union Against Tuberculosis and Lung Disease
Start Page
373
End Page
380
Journal / Book Title
International Journal of Tuberculosis and Lung Disease
Volume
27
Issue
5
Replaces
10044/1/103976
Copyright Statement
© 2023 The Author(s).
Identifier
https://www.ingentaconnect.com/content/iuatld/ijtld/2023/00000027/00000005/art00006;jsessionid=1lafqtuforf49.x-ic-live-01
Publication Status
Published
Date Publish Online
2023-05-01