Lung clearance index (LCI) and genotype-phenotype correlations in Primary Ciliary Dyskinesia (PCD)
File(s)acceptedLung clearance index and genotype.docx (30.96 KB)
Accepted version
Author(s)
Type
Conference Paper
Abstract
Introduction and objectives Mutation type may affect clinical phenotype in PCD, as shown by differences in forced expiratory volume in 1 s (FEV1) (AJRCCM 2015;191:316–324). LCI, measured using multi-breath washout (MBW) is raised in PCD (AJRCCM 2013;188:545–549) but the relative sensitivities of the two physiological measurements is disputed (Thorax 2015;70:339–345, and 305–306). We hypothesised that LCI would be more sensitive to genotype-phenotype differences in PCD.
Date Issued
2015-12-02
Date Acceptance
2015-12-02
Citation
Thorax, 2015, 70 (Suppl 3), pp.A116-A117
ISSN
0040-6376
Publisher
BMJ Publishing Group
Start Page
A116
End Page
A117
Journal / Book Title
Thorax
Volume
70
Issue
Suppl 3
Copyright Statement
© 2015 The Author(s). This article has been accepted for publication in Thorax following peer review. The definitive copyedited, typeset version Thorax 2015;70:A116-A117 doi:10.1136/thoraxjnl-2015-207770.219 is available online at: https://dx.doi.org/10.1136/thoraxjnl-2015-207770.219
Sponsor
NIHR
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000365353600220&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Source
Winter Meeting of the British-Thoracic-Society
Subjects
Science & Technology
Life Sciences & Biomedicine
Respiratory System
1103 Clinical Sciences
Publication Status
Published
Start Date
2015-12-02
Finish Date
2015-12-04
Coverage Spatial
London, ENGLAND