Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications.
File(s)
Published version
Author(s)
Type
Journal Article
Abstract
The first ever demonstration of temporal focusing with Short Wave InfraRed (SWIR) excitation and emission is demonstrated, achieving a penetration depth of 500µm in brain tissue. This is substantially deeper than the highest previously-reported values for temporal focusing imaging in brain tissue, and demonstrates the value of these optimized wavelengths for neurobiological applications.
Date Issued
2019-04-25
Date Acceptance
2019-04-05
Citation
Journal of Physics D: Applied Physics, 2019, 52 (26)
ISSN
0022-3727
Publisher
IOP Publishing
Journal / Book Title
Journal of Physics D: Applied Physics
Volume
52
Issue
26
Copyright Statement
© 2019 IOP Publishing Ltd. Original content from this work may be used under the terms of the Creative Commons Attribution 3.0 ( https://creativecommons.org/licenses/by/3.0/ ) licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI.
Subjects
Science & Technology
Physical Sciences
Physics, Applied
Physics
temporal focusing
multiphoton microscopy
quantum dots
fluorescence microscopy
neurophotonics
QUANTUM DOTS
Applied Physics
02 Physical Sciences
09 Engineering
Publication Status
Published
Article Number
264001