A cross-sectional MR study of body fat volumes and distribution in chronic schizophrenia
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Supporting information
Author(s)
Osimo, Emanuele
Brugger, Stefan
Thomas, Emma Louise
Howes, Oliver
Type
Journal Article
Abstract
People with schizophrenia show higher risk for abdominal obesity than the general population, which could contribute to excess mortality. However, it is unclear whether this is driven by alterations in abdominal fat partitioning. Here, we test the hypothesis that individuals with schizophrenia show a higher proportion of visceral to total body fat measured using magnetic resonance imaging (MRI). We recruited 38 participants with schizophrenia and 38 healthy controls matched on age, sex, ethnicity and body mass index. We found no significant differences in body fat distribution between groups, suggesting that increased abdominal obesity in schizophrenia is not associated with altered fat distribution.
Date Issued
2022-03-18
Date Acceptance
2022-02-02
Citation
npj Schizophrenia, 2022, 8
ISSN
2334-265X
Publisher
Nature Research
Journal / Book Title
npj Schizophrenia
Volume
8
Copyright Statement
© The Author(s) 2022. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
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Sponsor
Medical Research Council (MRC)
Grant Number
N/A
Publication Status
Published
Article Number
ARTN 24