Single-heartbeat cardiac cine imaging via jointly regularized non-rigid motion corrected reconstruction
File(s)
Published version
Author(s)
Type
Journal Article
Abstract
PURPOSE: Develop a novel approach for 2D breath-hold cardiac cine from a single heartbeat, by combining cardiac motion corrected reconstructions and non-rigidly aligned patch-based regularization. METHODS: Conventional cardiac cine imaging is obtained via motion resolved reconstructions of data acquired over multiple heartbeats. Here, we achieve single-heartbeat cine imaging by incorporating non-rigid cardiac motion correction into the reconstruction of each cardiac phase, in conjunction with a motion-aligned patch-based regularization. The proposed Motion Corrected CINE (MC-CINE) incorporates all acquired data into the reconstruction of each (motion corrected) cardiac phase, resulting in a better posed problem than motion resolved approaches. MC-CINE was compared to iterative SENSE and XD-GRASP in fourteen healthy subjects in terms of image sharpness, reader scoring (1-5 range) and reader ranking (1-9 range) of image quality, and single-slice left ventricular assessment. RESULTS: MC-CINE was significantly superior to both iterative SENSE and XD-GRASP using 20, 2 and 1 heartbeat(s). Iterative SENSE, XD-GRASP and MC-CINE achieved sharpness of 74%, 74% and 82% using 20 heartbeats, and 53%, 66% and 82% with 1 heartbeat, respectively. Corresponding results for reader scores were 4.0, 4.7 and 4.9, with 20 heartbeats, and 1.1, 3.0 and 3.9 with 1 heartbeat. Corresponding results for reader rankings were 5.3, 7.3 and 8.6 with 20 heartbeats, and 1.0, 3.2 and 5.4 with 1 heartbeat. MC-CINE using a single heartbeat presented non-significant differences in image quality to iterative SENSE with 20 heartbeats. MC-CINE and XD-GRASP at one heartbeat both presented a non-significant negative bias of <2% in ejection fraction relative to the reference iterative SENSE. CONCLUSION: The proposed MC-CINE significantly improves image quality relative to iterative SENSE and XD-GRASP, enabling 2D cine from a single heartbeat.
Date Issued
2023-09
Date Acceptance
2023-03-26
Citation
NMR in Biomedicine, 2023, 36 (9), pp.1-16
ISSN
0952-3480
Publisher
Wiley
Start Page
1
End Page
16
Journal / Book Title
NMR in Biomedicine
Volume
36
Issue
9
Copyright Statement
© 2023 The Authors. NMR in Biomedicine published by John Wiley & Sons Ltd.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
License URL
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/36999225
Subjects
Cardiac MR
CINE
Compressed Sensing
Motion Correction
Single-heartbeat
Publication Status
Published
Coverage Spatial
England
Article Number
e4942
Date Publish Online
2023-03-30