Neoantigens in ovarian cancer: embarrassment of riches or needles in a haystack?
File(s)
Accepted version
Author(s)
McNeish, IA
Type
Journal Article
Abstract
Comprehensive genomic and transcriptomic analysis demonstrates that tumor-infiltrating T lymphocytes that react to mutated neo-epitopes could be identified in recurrent ovarian cancer. Two of these T cell populations reacted against TP53 hotspot missense mutations that are present in a wide variety of malignancies.
Date Issued
2018-11-01
Date Acceptance
2018-06-22
Citation
Clinical Cancer Research, 2018, 24 (22), pp.5493-5495
ISSN
1078-0432
Publisher
American Association for Cancer Research
Start Page
5493
End Page
5495
Journal / Book Title
Clinical Cancer Research
Volume
24
Issue
22
Copyright Statement
©2018, American Association for Cancer Research.
Sponsor
Imperial College Healthcare NHS Trust- BRC Funding
Cancer Research UK
Grant Number
RDB01
RG71079
Subjects
Science & Technology
Life Sciences & Biomedicine
Oncology
Oncology & Carcinogenesis
1112 Oncology and Carcinogenesis
Publication Status
Published
Date Publish Online
2018-07-06