MRI for noninvasive thermometry
File(s)
Accepted version
Author(s)
Kardoulaki, Evdokia M
Syms, Richard RA
Young, Ian R
Type
Journal Article
Abstract
MRI was recognized for its potential use as a noninvasive in vivo thermometer 30 years ago. Today, the most popular application of MR thermometry is the guidance of thermal therapies for the treatment of cancer and other pathologies. These minimally invasive operations are routinely performed on patients who are not eligible for surgery in approximately 40 medical centers globally. The aim is to deliver or abduct thermal energy in order to cause local tissue necrosis or to sensitize a lesion to chemotherapy or radiotherapy without causing harm to the surrounding healthy tissue. Here we explain the principles of operation of MR thermometry and provide a critical review of the proposed methods, highlighting remaining fundamental and technical issues as well as recent progress. Emphasis is placed on hardware advances (RF receivers) for improved signal-to-noise ratio (SNR) which would lead to better accuracy, spatiotemporal resolution, and precise calibration. We conclude with a general outlook for the field.
Date Issued
2016-06-15
Date Acceptance
2016-06-15
Citation
eMagRes, 2016, 5 (2), pp.1203-1217
ISSN
2055-6101
Publisher
WILEY-BLACKWELL
Start Page
1203
End Page
1217
Journal / Book Title
eMagRes
Volume
5
Issue
2
Copyright Statement
© 2016 John Wiley & Sons, Ltd. All rights reserved. This is the pre-peer reviewed version of the following article, which has been published in final form at https://onlinelibrary.wiley.com/doi/abs/10.1002/9780470034590.emrstm1103
Subjects
Science & Technology
Technology
Spectroscopy
MR thermometry
temperature
laser ablation
focused ultrasound
hyperthermia
PRF fat
microcoils
SNR
cryotherapy
INTENSITY FOCUSED ULTRASOUND
LASER-INDUCED THERMOTHERAPY
INTERSTITIAL THERMAL THERAPY
MAGNETIC-RESONANCE-SPECTROSCOPY
WEIGHTED IMAGING THERMOMETRY
HUMAN BRAIN TEMPERATURE
IN-VIVO
CHEMICAL-SHIFT
EX-VIVO
SUSCEPTIBILITY CHANGES
Publication Status
Published