Mother-to-child transmission of hepatitis B: What more needs to be done to eliminate it around the world?
File(s)JVH review_accepted version_August 2019.pdf (227.2 KB)
Accepted version
Author(s)
Nayagam, Shevanthi
Shimakawa, Yusuke
Lemoine, Maud
Type
Journal Article
Abstract
Mother‐to‐child transmission (MTCT) of hepatitis B virus (HBV) is a key component of the hepatitis B burden worldwide. Despite its efficacy to prevent HBV transmission, infant vaccination is not enough to control HBV MTCT. Additional efforts are urgently needed to evaluate and scale‐up preventive strategies especially in endemic countries, which are most affected. This review highlights the efficacy and barriers of the currently validated measures for the prevention of HBV MTCT and proposes alternatives adapted to resource‐limited settings to eventually achieve HBV elimination worldwide.
Date Issued
2020-04
Date Acceptance
2019-08-12
Citation
Journal of Viral Hepatitis, 2020, 27 (4), pp.342-349
ISSN
1345-2533
Publisher
Wiley
Start Page
342
End Page
349
Journal / Book Title
Journal of Viral Hepatitis
Volume
27
Issue
4
Copyright Statement
© 2019 John Wiley & Sons Ltd. This is the accepted version of the following article: Nayagam, S, Shimakawa, Y, Lemoine, M. Mother‐to‐child transmission of hepatitis B: What more needs to be done to eliminate it around the world? J Viral Hepat. 2019; 00: 1– 8, which has been published in final form at https://doi.org/10.1111/jvh.13231
Sponsor
Medical Research Council (MRC)
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000508630400001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Grant Number
MR/R015600/1
Subjects
Science & Technology
Life Sciences & Biomedicine
Gastroenterology & Hepatology
Infectious Diseases
Virology
elimination
HBV
mother-to-child transmission
prevention
vaccine
COST-EFFECTIVENESS ANALYSIS
PREVENT PERINATAL TRANSMISSION
TENOFOVIR DISOPROXIL FUMARATE
CONTROLLED TEMPERATURE CHAIN
SINGLE-USE INJECTION
VIRUS INFECTION
E-ANTIGEN
VERTICAL TRANSMISSION
INFANT TRANSMISSION
ECONOMIC-EVALUATION
Publication Status
Published online
Date Publish Online
2019-11-07