The Tan-Lu fault (TLF) separates the Dabie and Sulu orogenic belts, well known for their ultra high pressure (UHP) metamorphic rocks in eastern China. We reinterpret one of the wide-angle seismic profiles traversing the TLF using traveltime tomography methods, and compare the results with the interpretation of three other seismic profiles across the TLF, to enable us to study the relationship of the five tectonic units comprising the North China plate (NCP), the Yangtze plate (YTZP), the TLF, the Dabie–Sulu orogenic belt (DSOB), and the ultra-high pressure metamorphic belt (UHPMB) that is exposed within the DSOB. The results demonstrate that there is strong lateral heterogeneity within the studied area. The TLF's penetrating depth deepens along a S–N direction. In the central section of the fault, the TLF can be traced to the middle crust but in the northern section it penetrates to the Moho. The average P-wave velocity in the UHPMB and DSOB is 0.1–0.4 km s-1 faster than that of the YTZP, NCP and TLF for upper crusts with depths <13 km, and 0.1–0.6 km s-1 slower for middle and lower crusts with depths >13 km. The bottom borders of the middle and lower crusts of the UHPMB and DSOB are apparently deeper than the other three tectonic units, and the Moho beneath UHPMB around Dabieshan may be deeper than 40 km. The general similarities of the crustal velocity structures between the Dabie and Sulu UHPMB may suggest a similar exhuming mechanism of UHP metamorphic rocks, before the large-scale TLF strike slip, driven by the subduction of the Yangtze block. The velocity gradient of the crust–mantle transition beneath the Sulu UHPMB implies the intrusion of basaltic melts from the upper mantle.