4-Membered ring carbocations: a positive development in the synthesis of 3,3-disubstituted oxetanes and azetidines
File(s)2023_192.pdf (546.57 KB)
Published version
Author(s)
Rojas, Juan J
Bull, James
Type
Journal Article
Abstract
4-Membered heterocycles are low molecular weight polar scaffolds with intriguing potential for drug discovery. Despite their unquestionable value, methods to access such heterocycles remain scant. Here, we describe the generation of oxetane- and azetidine- benzylic carbocations as a general strategy to access valuable 3,3-disubstituted derivatives.
Date Issued
2023-04-26
Date Acceptance
2023-02-27
Citation
CHIMIA, 2023, 77 (4), pp.192-195
ISSN
2673-2424
Publisher
Schweizerische Chemische Gesellschaft
Start Page
192
End Page
195
Journal / Book Title
CHIMIA
Volume
77
Issue
4
Copyright Statement
© J. J. Rojas, J. A. Bull. This work is licensed under a Creative Commons Attribution 4.0 International License. The material may not
be used for commercial purposes.
The license is subject to the CHIMIA terms and conditions:
(https://chimia.ch/chimia/about).
The definitive version of this article is the electronic one that can be
found at https://doi.org/10.2533/chimia.2023.192
be used for commercial purposes.
The license is subject to the CHIMIA terms and conditions:
(https://chimia.ch/chimia/about).
The definitive version of this article is the electronic one that can be
found at https://doi.org/10.2533/chimia.2023.192
License URL
Identifier
https://chimia.ch/chimia/article/view/2023_192
Publication Status
Published
Date Publish Online
2023-04-26