MARDy: mycology antifungal resistance database
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Published version
Author(s)
Type
Journal Article
Abstract
Summary:
The increase of antifungal drug resistance is a major global human health concern and
threatens agriculture and food security; in order to tackle these concerns, it is important to understand
the mechanisms that cause antifungal resistance. The curated Mycology Antifungal Resistance Database
(MARDy) is a web-service of antifungal drug resistance mechanisms, including amino acid substitutions,
tandem repeat sequences and genome ploidy. MARDy is implemented on a Linux, Apache, MySQL and
PHP web development platform and includes a local installation of BLASTn of the database of curated
genes.
Availability and implementation:
MARDy can be accessed at http://www.mardy.net and is free to
use. The complete database can be retrieved, ordered by organism, gene and drug. Missing or new
mycological antifungal resistance data can be relayed to the development team through a contribute entry
form.
The increase of antifungal drug resistance is a major global human health concern and
threatens agriculture and food security; in order to tackle these concerns, it is important to understand
the mechanisms that cause antifungal resistance. The curated Mycology Antifungal Resistance Database
(MARDy) is a web-service of antifungal drug resistance mechanisms, including amino acid substitutions,
tandem repeat sequences and genome ploidy. MARDy is implemented on a Linux, Apache, MySQL and
PHP web development platform and includes a local installation of BLASTn of the database of curated
genes.
Availability and implementation:
MARDy can be accessed at http://www.mardy.net and is free to
use. The complete database can be retrieved, ordered by organism, gene and drug. Missing or new
mycological antifungal resistance data can be relayed to the development team through a contribute entry
form.
Date Issued
2018-09-15
Date Acceptance
2018-03-24
Citation
Bioinformatics, 2018, 34 (18), pp.3233-3234
ISSN
1367-4803
Publisher
Oxford University Press (OUP)
Start Page
3233
End Page
3234
Journal / Book Title
Bioinformatics
Volume
34
Issue
18
Copyright Statement
© The Author(s) 2018. Published by Oxford University Press.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/
4.0/), which permits
unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/
4.0/), which permits
unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Sponsor
Medical Research Council (MRC)
Wellcome Trust
Grant Number
MR/K000373/1
105603/Z/14/Z
Subjects
Science & Technology
Life Sciences & Biomedicine
Technology
Physical Sciences
Biochemical Research Methods
Biotechnology & Applied Microbiology
Computer Science, Interdisciplinary Applications
Mathematical & Computational Biology
Statistics & Probability
Biochemistry & Molecular Biology
Computer Science
Mathematics
ASPERGILLUS-FUMIGATUS
Infectious Diseases
Mycology
Veterinary Sciences
01 Mathematical Sciences
06 Biological Sciences
08 Information And Computing Sciences
Bioinformatics
Publication Status
Published
Date Publish Online
2018-04-20