Reduced efficacy of praziquantel against Schistosoma mansoni is associated with multiple-rounds of mass drug administration
File(s)
Accepted version
Published version
Author(s)
Type
Journal Article
Abstract
The efficacy of praziquantel against Schistosoma mansoni was significantly lower in Ugandan schools that had received more prior rounds of mass drug administration, as determined by fitting a statistical model to parasite egg counts before and after treatment.
Date Issued
2016-07-28
Date Acceptance
2016-07-21
Citation
Clinical Infectious Diseases, 2016, 63 (9), pp.1151-1159
ISSN
1537-6591
Publisher
Oxford University Press (OUP)
Start Page
1151
End Page
1159
Journal / Book Title
Clinical Infectious Diseases
Volume
63
Issue
9
Copyright Statement
© The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
License URL
Sponsor
World Health Organization
World Health Organization (Switzerland)
Grant Number
World Health Organization
2015/540029-0
Subjects
anthelmintic efficacy
generalized linear mixed model
parasite
praziquantel
schistosomiasis
Microbiology
06 Biological Sciences
11 Medical And Health Sciences
Publication Status
Published