Dataset of the human homologues and orthologues of lipid-metabolic genes identified as DAF-16 targets and their roles in lipid and energy metabolism
File(s)
Author(s)
Fan, LY
Saavedra Garcia, P
Lam, EW
Type
Journal Article
Abstract
The data presented in this article are related to the review article entitled ‘Unravelling the role of fatty acid metabolism in cancer through the FOXO3-FOXM1 axis’ (Saavedra-Garcia et al., 2017) [24]. Here, we have matched the DAF-16/FOXO3 downstream genes with their respective human orthologues and reviewed the roles of these targeted genes in FA metabolism. The list of genes listed in this article are precisely selected from literature reviews based on their functions in mammalian FA metabolism. The nematode Caenorhabditis elegans gene orthologues of the genes are obtained from WormBase, the online biological database of C. elegans. This dataset has not been uploaded to a public repository yet.
Date Issued
2017-03-08
Date Acceptance
2017-02-28
Citation
Data in Brief, 2017, 11, pp.606-610
URI
DOI
ISSN
2352-3409
Publisher
Elsevier
Start Page
606
End Page
610
Journal / Book Title
Data in Brief
Volume
11
Copyright Statement
© 2017 The Authors. Published by E
lsevier Inc. This is an open
access article under the CC BY license
(http://creativecommons.org/licenses/by/4.0/).
Sponsor
Medical Research Council (MRC)
Imperial College Trust
Grant Number
MR/N012097/1
WSCC_P66361
Subjects
ACAA2, Acetyl-CoA acetyltransferase 2
ACACA, Acetyl-CoA carboxylase
ACAD8, Acyl-CoA dehydrogenase family member 8
ACADM, Acyl-CoA dehydrogenase C4 to C12 straight chain
ACOX, Acyl-CoA oxidase
ACSL3/4, Acyl-CoA synthetase long-chain family member 3/4
ACSS, Acyl-CoA synthetase short-chain family member
CPT2, Carnitine palmitoyltransferase II
Caenorhabditis elegans
DAF-16
DAG, Diacylglycerol
DGAT, Diacylglycerol O-acyltransferase
ECHS1, Short-chain enoyl-CoA hydratase 1
ELOVL1, Elongation of very long chain fatty acids protein 1
FA, fatty acid
FADS2, Fatty acid desaturase 2
FASN, Fatty acid synthase
FATP4, Fatty acid transport protein 4
FOX, Forkhead box
FOXM1
FOXO3
HADH, Hydroxyacyl-coenzyme A dehydrogenase
HADHA, Hydroxyacyl-CoA dehydrogenase/3-Ketoacyl-CoA thiolase/Enoyl-CoA hydratase, alpha subunit
LCFA, Long chain fatty acid
Lipid metabolism
MLYCD, Malonyl-CoA decarboxylase
MOGAT1/2, Monoacylglycerol O-acyltransferase 1/2
PNPLA, patatin like phospholipase domain containing
PUFA, polyunsaturated fatty acid
SCD1/5, Stearoyl-CoA desaturase 1/5
TAG, triacylglycerol
TCA, Tricarboxylic acid
VLCFA, Very long chain fatty acid.
Publication Status
Published